Clinico-epidemiological features of the hospitalized patients with 2009 pandemic influenza A (H1N1) virus infection in Saurashtra region, India (September, 2009 to February, 2010)

The first case of 2009 pandemic influenza A (H1N1) virus infection in India was reported in May, 2009 and in Saurashtra region in August, 2009. We describe the clinico-epidemiological characteristics of patients who were hospitalized with 2009 influenza A (H1N1) infection in Saurashtra region. From...

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Bibliographic Details
Published in:Lung India 2011-01, Vol.28 (1), p.11-16
Main Authors: Chudasama, Rajesh K, Patel, Umed V, Verma, Pramod B, Amin, Chikitsa D, Savaria, Dinkar, Ninama, Rakesh, Fichadiya, Nilesh
Format: Article
Language:English
Subjects:
Antibiotics
Data collection
Disease control
Epidemiologic information
H1N1 subtype
Hospitalization
Hospitals
Illnesses
influenza A virus
Mortality
Original
Pandemics
Pregnancy
reverse transcriptase polymerase chain reaction
Swine flu
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Summary:The first case of 2009 pandemic influenza A (H1N1) virus infection in India was reported in May, 2009 and in Saurashtra region in August, 2009. We describe the clinico-epidemiological characteristics of patients who were hospitalized with 2009 influenza A (H1N1) infection in Saurashtra region. From September, 2009 to February, 2010, we observed 274 persons infected with 2009 influenza A (H1N1) virus who were admitted in different hospitals in Rajkot city. Real-time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) testing was used to confirm infection; the clinico-epidemiological features of the disease were closely monitored. Of 274 patients, median age was 29.5 years, and 51.5% were males. Only 1.1% patients had recent travel history to infected region. Median time of five days was observed from onset of illness to influenza A (H1N1) diagnosis, while median time of six days reported for hospital stay. All admitted patients received oseltamivir drug, but only 16.1% received it within two days of onset of illness. One fourth of admitted patients were expired. The most common symptoms were cough (96.7%), fever (92%), sore throat and shortness of breathing, and coexisting conditions including diabetes mellitus (9.9%), hypertension (8.8%), chronic pulmonary diseases (5.5%) and pregnancy (5.5%) (P
ISSN:0970-2113
0974-598X
DOI:10.4103/0970-2113.76294