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Internet based intervention (Emotion Regulation Individual Therapy for Adolescents) as add‐on to treatment as usual versus treatment as usual for non‐suicidal self‐injury in adolescent outpatients: The TEENS randomised feasibility trial
Background Non‐suicidal self‐injury (NSSI) is common in adolescents receiving psychiatric treatment and is a significant risk factor for suicidal behavior. There are few randomised clinical trials assessing interventions for NSSI in youth, and knowledge about internet‐delivered interventions is limi...
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Published in: | JCPP advances 2022-12, Vol.2 (4), p.e12115-n/a |
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creator | Morthorst, Britt Olsen, Markus Harboe Jakobsen, Janus Christian Lindschou, Jane Gluud, Christian Heinrichsen, Michella Møhl, Bo Rubæk, Lotte Ojala, Olivia Hellner, Clara Bjureberg, Johan Pagsberg, Anne Katrine |
description | Background
Non‐suicidal self‐injury (NSSI) is common in adolescents receiving psychiatric treatment and is a significant risk factor for suicidal behavior. There are few randomised clinical trials assessing interventions for NSSI in youth, and knowledge about internet‐delivered interventions is limited.
Objective
We assessed the feasibility of Internet based Emotion Regulation Individual Therapy for Adolescents (ERITA) in psychiatric outpatients aged 13–17 years who engaged in NSSI.
Method
A randomised clinical feasibility trial with a parallel group design. Non‐suicidal self‐injury engaging patients were recruited from Child and Adolescent Mental Health Outpatient Services in the Capital Region of Denmark from May to October 2020. ERITA was provided as add‐on to treatment as usual (TAU). ERITA is a therapist‐guided, internet‐based program of emotion regulation and skills training involving a parent. The control intervention was TAU. Feasibility outcomes were the proportion who completed follow‐up interviews at end of intervention; proportion of eligible patients who participated in the trial; proportion of participants completing ERITA. We further investigated relevant exploratory outcomes, including adverse risk‐related events.
Results
We included 30 adolescent participants, 15 in each group (ERITA vs. Treatment as usual). 90% (95% CI, 72%–97%) of the participants completed post‐treatment interviews; 54% (95% CI, 40%–67%) of the eligible participants were included and randomised; and 87% (95% CI, 58%–98%) of the participants completed at least six out of 11 ERITA modules. We identified no difference for the primary exploratory clinical outcome of NSSI between the two groups.
Conclusion
There are few randomised clinical trials assessing interventions for NSSI in youth, and knowledge about internet‐delivered interventions is limited. Based on our results we conclude that a large‐scale trial seems feasible and warranted.
Internet based intervention for non‐suicidal self‐injury (ERITA) is tested in Child and Adolescent Mental Health Services in Denmark and found feasible warranting for further investigation in a large‐scale trial. |
doi_str_mv | 10.1002/jcv2.12115 |
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Non‐suicidal self‐injury (NSSI) is common in adolescents receiving psychiatric treatment and is a significant risk factor for suicidal behavior. There are few randomised clinical trials assessing interventions for NSSI in youth, and knowledge about internet‐delivered interventions is limited.
Objective
We assessed the feasibility of Internet based Emotion Regulation Individual Therapy for Adolescents (ERITA) in psychiatric outpatients aged 13–17 years who engaged in NSSI.
Method
A randomised clinical feasibility trial with a parallel group design. Non‐suicidal self‐injury engaging patients were recruited from Child and Adolescent Mental Health Outpatient Services in the Capital Region of Denmark from May to October 2020. ERITA was provided as add‐on to treatment as usual (TAU). ERITA is a therapist‐guided, internet‐based program of emotion regulation and skills training involving a parent. The control intervention was TAU. Feasibility outcomes were the proportion who completed follow‐up interviews at end of intervention; proportion of eligible patients who participated in the trial; proportion of participants completing ERITA. We further investigated relevant exploratory outcomes, including adverse risk‐related events.
Results
We included 30 adolescent participants, 15 in each group (ERITA vs. Treatment as usual). 90% (95% CI, 72%–97%) of the participants completed post‐treatment interviews; 54% (95% CI, 40%–67%) of the eligible participants were included and randomised; and 87% (95% CI, 58%–98%) of the participants completed at least six out of 11 ERITA modules. We identified no difference for the primary exploratory clinical outcome of NSSI between the two groups.
Conclusion
There are few randomised clinical trials assessing interventions for NSSI in youth, and knowledge about internet‐delivered interventions is limited. Based on our results we conclude that a large‐scale trial seems feasible and warranted.
Internet based intervention for non‐suicidal self‐injury (ERITA) is tested in Child and Adolescent Mental Health Services in Denmark and found feasible warranting for further investigation in a large‐scale trial.</description><identifier>ISSN: 2692-9384</identifier><identifier>EISSN: 2692-9384</identifier><identifier>DOI: 10.1002/jcv2.12115</identifier><identifier>PMID: 37431416</identifier><language>eng</language><publisher>United States: John Wiley & Sons, Inc</publisher><subject>Behavior modification ; Child & adolescent mental health ; Child & adolescent psychiatry ; Clinical trials ; Cognition & reasoning ; emotion regulation individual therapy for adolescents ; Emotional regulation ; ERITA ; Feasibility ; feasibility trial ; Government archives ; Guardians ; Health services ; Internet ; internet based intervention ; Intervention ; Mental disorders ; Mental health care ; non‐suicidal self‐injury ; Original ; Patients ; Personality disorders ; randomised ; Self destructive behavior ; Suicides & suicide attempts</subject><ispartof>JCPP advances, 2022-12, Vol.2 (4), p.e12115-n/a</ispartof><rights>2022 The Authors. JCPP Advances published by John Wiley & Sons Ltd on behalf of Association for Child and Adolescent Mental Health.</rights><rights>2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the "License"). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c5095-80a20eba86d5b2089f1dc05b70c38fd4aa818feda50316ba40b467b34f1dcf1f3</cites><orcidid>0000-0003-2747-9990 ; 0000-0002-3599-3781</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242949/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/3090611889?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,11561,25752,27923,27924,37011,37012,38515,43894,44589,46051,46475,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37431416$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:237431416$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Morthorst, Britt</creatorcontrib><creatorcontrib>Olsen, Markus Harboe</creatorcontrib><creatorcontrib>Jakobsen, Janus Christian</creatorcontrib><creatorcontrib>Lindschou, Jane</creatorcontrib><creatorcontrib>Gluud, Christian</creatorcontrib><creatorcontrib>Heinrichsen, Michella</creatorcontrib><creatorcontrib>Møhl, Bo</creatorcontrib><creatorcontrib>Rubæk, Lotte</creatorcontrib><creatorcontrib>Ojala, Olivia</creatorcontrib><creatorcontrib>Hellner, Clara</creatorcontrib><creatorcontrib>Bjureberg, Johan</creatorcontrib><creatorcontrib>Pagsberg, Anne Katrine</creatorcontrib><title>Internet based intervention (Emotion Regulation Individual Therapy for Adolescents) as add‐on to treatment as usual versus treatment as usual for non‐suicidal self‐injury in adolescent outpatients: The TEENS randomised feasibility trial</title><title>JCPP advances</title><addtitle>JCPP Adv</addtitle><description>Background
Non‐suicidal self‐injury (NSSI) is common in adolescents receiving psychiatric treatment and is a significant risk factor for suicidal behavior. There are few randomised clinical trials assessing interventions for NSSI in youth, and knowledge about internet‐delivered interventions is limited.
Objective
We assessed the feasibility of Internet based Emotion Regulation Individual Therapy for Adolescents (ERITA) in psychiatric outpatients aged 13–17 years who engaged in NSSI.
Method
A randomised clinical feasibility trial with a parallel group design. Non‐suicidal self‐injury engaging patients were recruited from Child and Adolescent Mental Health Outpatient Services in the Capital Region of Denmark from May to October 2020. ERITA was provided as add‐on to treatment as usual (TAU). ERITA is a therapist‐guided, internet‐based program of emotion regulation and skills training involving a parent. The control intervention was TAU. Feasibility outcomes were the proportion who completed follow‐up interviews at end of intervention; proportion of eligible patients who participated in the trial; proportion of participants completing ERITA. We further investigated relevant exploratory outcomes, including adverse risk‐related events.
Results
We included 30 adolescent participants, 15 in each group (ERITA vs. Treatment as usual). 90% (95% CI, 72%–97%) of the participants completed post‐treatment interviews; 54% (95% CI, 40%–67%) of the eligible participants were included and randomised; and 87% (95% CI, 58%–98%) of the participants completed at least six out of 11 ERITA modules. We identified no difference for the primary exploratory clinical outcome of NSSI between the two groups.
Conclusion
There are few randomised clinical trials assessing interventions for NSSI in youth, and knowledge about internet‐delivered interventions is limited. Based on our results we conclude that a large‐scale trial seems feasible and warranted.
Internet based intervention for non‐suicidal self‐injury (ERITA) is tested in Child and Adolescent Mental Health Services in Denmark and found feasible warranting for further investigation in a large‐scale trial.</description><subject>Behavior modification</subject><subject>Child & adolescent mental health</subject><subject>Child & adolescent psychiatry</subject><subject>Clinical trials</subject><subject>Cognition & reasoning</subject><subject>emotion regulation individual therapy for adolescents</subject><subject>Emotional regulation</subject><subject>ERITA</subject><subject>Feasibility</subject><subject>feasibility trial</subject><subject>Government archives</subject><subject>Guardians</subject><subject>Health services</subject><subject>Internet</subject><subject>internet based intervention</subject><subject>Intervention</subject><subject>Mental disorders</subject><subject>Mental health care</subject><subject>non‐suicidal self‐injury</subject><subject>Original</subject><subject>Patients</subject><subject>Personality disorders</subject><subject>randomised</subject><subject>Self destructive behavior</subject><subject>Suicides & suicide attempts</subject><issn>2692-9384</issn><issn>2692-9384</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>COVID</sourceid><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNp9ks1uEzEQx1cIRKvSCw-ALHEpSCn-2i8uVRUFCKpAgsDVml17UwfHDvZuqtx4BJ6RR-AJsJO0ahDi5PHMb_4zHk-WPSX4nGBMXy3aNT0nlJD8QXZMi5qOalbxh_fso-w0hAWOcE4YyfPH2RErOSOcFMfZ76ntlbeqRw0EJZFO17WyvXYWnU2Wbmt8UvPBwNacWqnXWg5g0OxaeVhtUOc8upTOqNDGxPACQUAg5a8fPyPfO9R7Bf0yhlJgCCl1rXwYwr8iScw6G5PDoFstoyso08W7tovBb2KHUfy2GHJDv4qNpbqvU0NoNpl8-Iw8WOmWOr2oUxB0o43uN7GeBvMke9SBCep0f55kX95MZuN3o6uPb6fjy6tRm-M6H1UYKFYNVIXMG4qruiOyxXlT4pZVneQAFak6JSHHjBQNcNzwomwYT1xHOnaSTXe60sFCrLxegt8IB1psHc7PBfhet0aJLv6MLAAwlcCbQsZapK0YMFqUbVGWUWu00wo3ajU0B2p717doKcF5zgmN_MWOj5GlkmlUHsxB2mHE6msxd2tBMOW05nVUONsrePd9UKEXcZytMgasckMQtGIFrcuK8Yg-_wtduMHbOFvBcI0LQqoqCb7cUa13IXjV3XVDsEirLNIqi-0qR_jZ_f7v0NvFjQDZATfaqM1_pMT78Ve6E_0DO-QIdw</recordid><startdate>202212</startdate><enddate>202212</enddate><creator>Morthorst, Britt</creator><creator>Olsen, Markus Harboe</creator><creator>Jakobsen, Janus Christian</creator><creator>Lindschou, Jane</creator><creator>Gluud, Christian</creator><creator>Heinrichsen, Michella</creator><creator>Møhl, Bo</creator><creator>Rubæk, Lotte</creator><creator>Ojala, Olivia</creator><creator>Hellner, Clara</creator><creator>Bjureberg, Johan</creator><creator>Pagsberg, Anne Katrine</creator><general>John Wiley & Sons, Inc</general><general>John Wiley and Sons Inc</general><general>Wiley</general><scope>24P</scope><scope>WIN</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7XB</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>COVID</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>M2M</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><scope>ADTPV</scope><scope>AOWAS</scope><scope>D8T</scope><scope>ZZAVC</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-2747-9990</orcidid><orcidid>https://orcid.org/0000-0002-3599-3781</orcidid></search><sort><creationdate>202212</creationdate><title>Internet based intervention (Emotion Regulation Individual Therapy for Adolescents) as add‐on to treatment as usual versus treatment as usual for non‐suicidal self‐injury in adolescent outpatients: The TEENS randomised feasibility trial</title><author>Morthorst, Britt ; Olsen, Markus Harboe ; Jakobsen, Janus Christian ; Lindschou, Jane ; Gluud, Christian ; Heinrichsen, Michella ; Møhl, Bo ; Rubæk, Lotte ; Ojala, Olivia ; Hellner, Clara ; Bjureberg, Johan ; Pagsberg, Anne Katrine</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5095-80a20eba86d5b2089f1dc05b70c38fd4aa818feda50316ba40b467b34f1dcf1f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Behavior modification</topic><topic>Child & adolescent mental health</topic><topic>Child & adolescent psychiatry</topic><topic>Clinical trials</topic><topic>Cognition & reasoning</topic><topic>emotion regulation individual therapy for adolescents</topic><topic>Emotional regulation</topic><topic>ERITA</topic><topic>Feasibility</topic><topic>feasibility trial</topic><topic>Government archives</topic><topic>Guardians</topic><topic>Health services</topic><topic>Internet</topic><topic>internet based intervention</topic><topic>Intervention</topic><topic>Mental disorders</topic><topic>Mental health care</topic><topic>non‐suicidal self‐injury</topic><topic>Original</topic><topic>Patients</topic><topic>Personality disorders</topic><topic>randomised</topic><topic>Self destructive behavior</topic><topic>Suicides & suicide attempts</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Morthorst, Britt</creatorcontrib><creatorcontrib>Olsen, Markus Harboe</creatorcontrib><creatorcontrib>Jakobsen, Janus Christian</creatorcontrib><creatorcontrib>Lindschou, Jane</creatorcontrib><creatorcontrib>Gluud, Christian</creatorcontrib><creatorcontrib>Heinrichsen, Michella</creatorcontrib><creatorcontrib>Møhl, Bo</creatorcontrib><creatorcontrib>Rubæk, Lotte</creatorcontrib><creatorcontrib>Ojala, Olivia</creatorcontrib><creatorcontrib>Hellner, Clara</creatorcontrib><creatorcontrib>Bjureberg, Johan</creatorcontrib><creatorcontrib>Pagsberg, Anne Katrine</creatorcontrib><collection>Wiley Online Library Open Access</collection><collection>Wiley Online Library Free Content</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Psychology Database (Alumni)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Coronavirus Research Database</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Psychology Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>SwePub</collection><collection>SwePub Articles</collection><collection>SWEPUB Freely available online</collection><collection>SwePub Articles full text</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>JCPP advances</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Morthorst, Britt</au><au>Olsen, Markus Harboe</au><au>Jakobsen, Janus Christian</au><au>Lindschou, Jane</au><au>Gluud, Christian</au><au>Heinrichsen, Michella</au><au>Møhl, Bo</au><au>Rubæk, Lotte</au><au>Ojala, Olivia</au><au>Hellner, Clara</au><au>Bjureberg, Johan</au><au>Pagsberg, Anne Katrine</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Internet based intervention (Emotion Regulation Individual Therapy for Adolescents) as add‐on to treatment as usual versus treatment as usual for non‐suicidal self‐injury in adolescent outpatients: The TEENS randomised feasibility trial</atitle><jtitle>JCPP advances</jtitle><addtitle>JCPP Adv</addtitle><date>2022-12</date><risdate>2022</risdate><volume>2</volume><issue>4</issue><spage>e12115</spage><epage>n/a</epage><pages>e12115-n/a</pages><issn>2692-9384</issn><eissn>2692-9384</eissn><abstract>Background
Non‐suicidal self‐injury (NSSI) is common in adolescents receiving psychiatric treatment and is a significant risk factor for suicidal behavior. There are few randomised clinical trials assessing interventions for NSSI in youth, and knowledge about internet‐delivered interventions is limited.
Objective
We assessed the feasibility of Internet based Emotion Regulation Individual Therapy for Adolescents (ERITA) in psychiatric outpatients aged 13–17 years who engaged in NSSI.
Method
A randomised clinical feasibility trial with a parallel group design. Non‐suicidal self‐injury engaging patients were recruited from Child and Adolescent Mental Health Outpatient Services in the Capital Region of Denmark from May to October 2020. ERITA was provided as add‐on to treatment as usual (TAU). ERITA is a therapist‐guided, internet‐based program of emotion regulation and skills training involving a parent. The control intervention was TAU. Feasibility outcomes were the proportion who completed follow‐up interviews at end of intervention; proportion of eligible patients who participated in the trial; proportion of participants completing ERITA. We further investigated relevant exploratory outcomes, including adverse risk‐related events.
Results
We included 30 adolescent participants, 15 in each group (ERITA vs. Treatment as usual). 90% (95% CI, 72%–97%) of the participants completed post‐treatment interviews; 54% (95% CI, 40%–67%) of the eligible participants were included and randomised; and 87% (95% CI, 58%–98%) of the participants completed at least six out of 11 ERITA modules. We identified no difference for the primary exploratory clinical outcome of NSSI between the two groups.
Conclusion
There are few randomised clinical trials assessing interventions for NSSI in youth, and knowledge about internet‐delivered interventions is limited. Based on our results we conclude that a large‐scale trial seems feasible and warranted.
Internet based intervention for non‐suicidal self‐injury (ERITA) is tested in Child and Adolescent Mental Health Services in Denmark and found feasible warranting for further investigation in a large‐scale trial.</abstract><cop>United States</cop><pub>John Wiley & Sons, Inc</pub><pmid>37431416</pmid><doi>10.1002/jcv2.12115</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0003-2747-9990</orcidid><orcidid>https://orcid.org/0000-0002-3599-3781</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Behavior modification Child & adolescent mental health Child & adolescent psychiatry Clinical trials Cognition & reasoning emotion regulation individual therapy for adolescents Emotional regulation ERITA Feasibility feasibility trial Government archives Guardians Health services Internet internet based intervention Intervention Mental disorders Mental health care non‐suicidal self‐injury Original Patients Personality disorders randomised Self destructive behavior Suicides & suicide attempts |
title | Internet based intervention (Emotion Regulation Individual Therapy for Adolescents) as add‐on to treatment as usual versus treatment as usual for non‐suicidal self‐injury in adolescent outpatients: The TEENS randomised feasibility trial |
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