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Internet based intervention (Emotion Regulation Individual Therapy for Adolescents) as add‐on to treatment as usual versus treatment as usual for non‐suicidal self‐injury in adolescent outpatients: The TEENS randomised feasibility trial

Background Non‐suicidal self‐injury (NSSI) is common in adolescents receiving psychiatric treatment and is a significant risk factor for suicidal behavior. There are few randomised clinical trials assessing interventions for NSSI in youth, and knowledge about internet‐delivered interventions is limi...

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Published in:JCPP advances 2022-12, Vol.2 (4), p.e12115-n/a
Main Authors: Morthorst, Britt, Olsen, Markus Harboe, Jakobsen, Janus Christian, Lindschou, Jane, Gluud, Christian, Heinrichsen, Michella, Møhl, Bo, Rubæk, Lotte, Ojala, Olivia, Hellner, Clara, Bjureberg, Johan, Pagsberg, Anne Katrine
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container_start_page e12115
container_title JCPP advances
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creator Morthorst, Britt
Olsen, Markus Harboe
Jakobsen, Janus Christian
Lindschou, Jane
Gluud, Christian
Heinrichsen, Michella
Møhl, Bo
Rubæk, Lotte
Ojala, Olivia
Hellner, Clara
Bjureberg, Johan
Pagsberg, Anne Katrine
description Background Non‐suicidal self‐injury (NSSI) is common in adolescents receiving psychiatric treatment and is a significant risk factor for suicidal behavior. There are few randomised clinical trials assessing interventions for NSSI in youth, and knowledge about internet‐delivered interventions is limited. Objective We assessed the feasibility of Internet based Emotion Regulation Individual Therapy for Adolescents (ERITA) in psychiatric outpatients aged 13–17 years who engaged in NSSI. Method A randomised clinical feasibility trial with a parallel group design. Non‐suicidal self‐injury engaging patients were recruited from Child and Adolescent Mental Health Outpatient Services in the Capital Region of Denmark from May to October 2020. ERITA was provided as add‐on to treatment as usual (TAU). ERITA is a therapist‐guided, internet‐based program of emotion regulation and skills training involving a parent. The control intervention was TAU. Feasibility outcomes were the proportion who completed follow‐up interviews at end of intervention; proportion of eligible patients who participated in the trial; proportion of participants completing ERITA. We further investigated relevant exploratory outcomes, including adverse risk‐related events. Results We included 30 adolescent participants, 15 in each group (ERITA vs. Treatment as usual). 90% (95% CI, 72%–97%) of the participants completed post‐treatment interviews; 54% (95% CI, 40%–67%) of the eligible participants were included and randomised; and 87% (95% CI, 58%–98%) of the participants completed at least six out of 11 ERITA modules. We identified no difference for the primary exploratory clinical outcome of NSSI between the two groups. Conclusion There are few randomised clinical trials assessing interventions for NSSI in youth, and knowledge about internet‐delivered interventions is limited. Based on our results we conclude that a large‐scale trial seems feasible and warranted. Internet based intervention for non‐suicidal self‐injury (ERITA) is tested in Child and Adolescent Mental Health Services in Denmark and found feasible warranting for further investigation in a large‐scale trial.
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There are few randomised clinical trials assessing interventions for NSSI in youth, and knowledge about internet‐delivered interventions is limited. Objective We assessed the feasibility of Internet based Emotion Regulation Individual Therapy for Adolescents (ERITA) in psychiatric outpatients aged 13–17 years who engaged in NSSI. Method A randomised clinical feasibility trial with a parallel group design. Non‐suicidal self‐injury engaging patients were recruited from Child and Adolescent Mental Health Outpatient Services in the Capital Region of Denmark from May to October 2020. ERITA was provided as add‐on to treatment as usual (TAU). ERITA is a therapist‐guided, internet‐based program of emotion regulation and skills training involving a parent. The control intervention was TAU. Feasibility outcomes were the proportion who completed follow‐up interviews at end of intervention; proportion of eligible patients who participated in the trial; proportion of participants completing ERITA. We further investigated relevant exploratory outcomes, including adverse risk‐related events. Results We included 30 adolescent participants, 15 in each group (ERITA vs. Treatment as usual). 90% (95% CI, 72%–97%) of the participants completed post‐treatment interviews; 54% (95% CI, 40%–67%) of the eligible participants were included and randomised; and 87% (95% CI, 58%–98%) of the participants completed at least six out of 11 ERITA modules. We identified no difference for the primary exploratory clinical outcome of NSSI between the two groups. Conclusion There are few randomised clinical trials assessing interventions for NSSI in youth, and knowledge about internet‐delivered interventions is limited. Based on our results we conclude that a large‐scale trial seems feasible and warranted. Internet based intervention for non‐suicidal self‐injury (ERITA) is tested in Child and Adolescent Mental Health Services in Denmark and found feasible warranting for further investigation in a large‐scale trial.</description><identifier>ISSN: 2692-9384</identifier><identifier>EISSN: 2692-9384</identifier><identifier>DOI: 10.1002/jcv2.12115</identifier><identifier>PMID: 37431416</identifier><language>eng</language><publisher>United States: John Wiley &amp; Sons, Inc</publisher><subject>Behavior modification ; Child &amp; adolescent mental health ; Child &amp; adolescent psychiatry ; Clinical trials ; Cognition &amp; reasoning ; emotion regulation individual therapy for adolescents ; Emotional regulation ; ERITA ; Feasibility ; feasibility trial ; Government archives ; Guardians ; Health services ; Internet ; internet based intervention ; Intervention ; Mental disorders ; Mental health care ; non‐suicidal self‐injury ; Original ; Patients ; Personality disorders ; randomised ; Self destructive behavior ; Suicides &amp; suicide attempts</subject><ispartof>JCPP advances, 2022-12, Vol.2 (4), p.e12115-n/a</ispartof><rights>2022 The Authors. 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Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c5095-80a20eba86d5b2089f1dc05b70c38fd4aa818feda50316ba40b467b34f1dcf1f3</cites><orcidid>0000-0003-2747-9990 ; 0000-0002-3599-3781</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242949/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/3090611889?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,11561,25752,27923,27924,37011,37012,38515,43894,44589,46051,46475,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37431416$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:237431416$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Morthorst, Britt</creatorcontrib><creatorcontrib>Olsen, Markus Harboe</creatorcontrib><creatorcontrib>Jakobsen, Janus Christian</creatorcontrib><creatorcontrib>Lindschou, Jane</creatorcontrib><creatorcontrib>Gluud, Christian</creatorcontrib><creatorcontrib>Heinrichsen, Michella</creatorcontrib><creatorcontrib>Møhl, Bo</creatorcontrib><creatorcontrib>Rubæk, Lotte</creatorcontrib><creatorcontrib>Ojala, Olivia</creatorcontrib><creatorcontrib>Hellner, Clara</creatorcontrib><creatorcontrib>Bjureberg, Johan</creatorcontrib><creatorcontrib>Pagsberg, Anne Katrine</creatorcontrib><title>Internet based intervention (Emotion Regulation Individual Therapy for Adolescents) as add‐on to treatment as usual versus treatment as usual for non‐suicidal self‐injury in adolescent outpatients: The TEENS randomised feasibility trial</title><title>JCPP advances</title><addtitle>JCPP Adv</addtitle><description>Background Non‐suicidal self‐injury (NSSI) is common in adolescents receiving psychiatric treatment and is a significant risk factor for suicidal behavior. There are few randomised clinical trials assessing interventions for NSSI in youth, and knowledge about internet‐delivered interventions is limited. Objective We assessed the feasibility of Internet based Emotion Regulation Individual Therapy for Adolescents (ERITA) in psychiatric outpatients aged 13–17 years who engaged in NSSI. Method A randomised clinical feasibility trial with a parallel group design. Non‐suicidal self‐injury engaging patients were recruited from Child and Adolescent Mental Health Outpatient Services in the Capital Region of Denmark from May to October 2020. ERITA was provided as add‐on to treatment as usual (TAU). ERITA is a therapist‐guided, internet‐based program of emotion regulation and skills training involving a parent. The control intervention was TAU. Feasibility outcomes were the proportion who completed follow‐up interviews at end of intervention; proportion of eligible patients who participated in the trial; proportion of participants completing ERITA. We further investigated relevant exploratory outcomes, including adverse risk‐related events. Results We included 30 adolescent participants, 15 in each group (ERITA vs. Treatment as usual). 90% (95% CI, 72%–97%) of the participants completed post‐treatment interviews; 54% (95% CI, 40%–67%) of the eligible participants were included and randomised; and 87% (95% CI, 58%–98%) of the participants completed at least six out of 11 ERITA modules. We identified no difference for the primary exploratory clinical outcome of NSSI between the two groups. Conclusion There are few randomised clinical trials assessing interventions for NSSI in youth, and knowledge about internet‐delivered interventions is limited. Based on our results we conclude that a large‐scale trial seems feasible and warranted. 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Olsen, Markus Harboe ; Jakobsen, Janus Christian ; Lindschou, Jane ; Gluud, Christian ; Heinrichsen, Michella ; Møhl, Bo ; Rubæk, Lotte ; Ojala, Olivia ; Hellner, Clara ; Bjureberg, Johan ; Pagsberg, Anne Katrine</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5095-80a20eba86d5b2089f1dc05b70c38fd4aa818feda50316ba40b467b34f1dcf1f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Behavior modification</topic><topic>Child &amp; adolescent mental health</topic><topic>Child &amp; adolescent psychiatry</topic><topic>Clinical trials</topic><topic>Cognition &amp; reasoning</topic><topic>emotion regulation individual therapy for adolescents</topic><topic>Emotional regulation</topic><topic>ERITA</topic><topic>Feasibility</topic><topic>feasibility trial</topic><topic>Government archives</topic><topic>Guardians</topic><topic>Health services</topic><topic>Internet</topic><topic>internet based intervention</topic><topic>Intervention</topic><topic>Mental disorders</topic><topic>Mental health care</topic><topic>non‐suicidal self‐injury</topic><topic>Original</topic><topic>Patients</topic><topic>Personality disorders</topic><topic>randomised</topic><topic>Self destructive behavior</topic><topic>Suicides &amp; 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There are few randomised clinical trials assessing interventions for NSSI in youth, and knowledge about internet‐delivered interventions is limited. Objective We assessed the feasibility of Internet based Emotion Regulation Individual Therapy for Adolescents (ERITA) in psychiatric outpatients aged 13–17 years who engaged in NSSI. Method A randomised clinical feasibility trial with a parallel group design. Non‐suicidal self‐injury engaging patients were recruited from Child and Adolescent Mental Health Outpatient Services in the Capital Region of Denmark from May to October 2020. ERITA was provided as add‐on to treatment as usual (TAU). ERITA is a therapist‐guided, internet‐based program of emotion regulation and skills training involving a parent. The control intervention was TAU. Feasibility outcomes were the proportion who completed follow‐up interviews at end of intervention; proportion of eligible patients who participated in the trial; proportion of participants completing ERITA. We further investigated relevant exploratory outcomes, including adverse risk‐related events. Results We included 30 adolescent participants, 15 in each group (ERITA vs. Treatment as usual). 90% (95% CI, 72%–97%) of the participants completed post‐treatment interviews; 54% (95% CI, 40%–67%) of the eligible participants were included and randomised; and 87% (95% CI, 58%–98%) of the participants completed at least six out of 11 ERITA modules. We identified no difference for the primary exploratory clinical outcome of NSSI between the two groups. Conclusion There are few randomised clinical trials assessing interventions for NSSI in youth, and knowledge about internet‐delivered interventions is limited. Based on our results we conclude that a large‐scale trial seems feasible and warranted. Internet based intervention for non‐suicidal self‐injury (ERITA) is tested in Child and Adolescent Mental Health Services in Denmark and found feasible warranting for further investigation in a large‐scale trial.</abstract><cop>United States</cop><pub>John Wiley &amp; Sons, Inc</pub><pmid>37431416</pmid><doi>10.1002/jcv2.12115</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0003-2747-9990</orcidid><orcidid>https://orcid.org/0000-0002-3599-3781</orcidid><oa>free_for_read</oa></addata></record>
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subjects Behavior modification
Child & adolescent mental health
Child & adolescent psychiatry
Clinical trials
Cognition & reasoning
emotion regulation individual therapy for adolescents
Emotional regulation
ERITA
Feasibility
feasibility trial
Government archives
Guardians
Health services
Internet
internet based intervention
Intervention
Mental disorders
Mental health care
non‐suicidal self‐injury
Original
Patients
Personality disorders
randomised
Self destructive behavior
Suicides & suicide attempts
title Internet based intervention (Emotion Regulation Individual Therapy for Adolescents) as add‐on to treatment as usual versus treatment as usual for non‐suicidal self‐injury in adolescent outpatients: The TEENS randomised feasibility trial
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