Profile of acute kidney injury after open heart surgeries in a tertiary care hospital

Our objective is to determine the incidence, etiology, risk factors and outcome of acute kidney injury (AKI) after open heart surgery. A prospective study was conducted on 62 patients who underwent open heart surgery and were followed-up for the development of AKI and to determine its incidence, eti...

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Bibliographic Details
Published in:Saudi journal of kidney diseases and transplantation 2015-11, Vol.26 (6), p.1177-1182
Main Authors: Rather, Fayaz A., Najar, Salim M., Wani, Imtiyaz A., Bhat, Hilal M., Ahangar, A. G., Mala, Hilal A.
Format: Article
Language:English
Subjects:
Acute Kidney Injury - epidemiology
Acute Kidney Injury - etiology
Acute Kidney Injury - mortality
Acute renal failure
Adolescent
Adult
Cardiac Surgical Procedures
Child
Child, Preschool
Complications
Complications and side effects
Diabetic Nephropathies - epidemiology
Diagnosis
Etiology
Female
Gout - epidemiology
Heart
Heart surgery
Humans
Hypertension - epidemiology
Incidence
Kidney diseases
Male
Middle Aged
Operative Time
Patient outcomes
Patients
Postoperative Complications - epidemiology
Prospective Studies
Risk Factors
Surgery
Tertiary Care Centers
Young Adult
الجراحة
الفشل الكلوي
القلب
المرضى
المضاعفات
علم الأمراض
مسببات الأمراض
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Summary:Our objective is to determine the incidence, etiology, risk factors and outcome of acute kidney injury (AKI) after open heart surgery. A prospective study was conducted on 62 patients who underwent open heart surgery and were followed-up for the development of AKI and to determine its incidence, etiology and outcome. Post-operative AKI was considered when the post-operative serum creatinine was >1.5 mg / dL or there was doubling of serum creatinine above the baseline (pre-operative) with a prior normal renal function. The incidence of AKI in the post-operative period in our study was 17.7 %. The common etiological factors for AKI in our study were sepsis, hypotension, prolonged need for ventilator and inotropic support and drugs given in the post-operative period. The important risk factors for the development of AKI in the post-operative period were hypertension, diabetes mellitus, gout, prolonged total bypass time and prolonged aortic cross–clamp time. The overall mortality in our study subjects was 11.3 % (seven of 62 died) and the mortality in the patients who developed post-operative AKI was 71.4 %.
ISSN:1319-2442
2320-3838
DOI:10.4103/1319-2442.168601