Carbapenem-resistant Pseudomonas aeruginosa outbreak in an intensive care unit of a teaching hospital

The genetic similarity of carbapenem-resistant Pseudomonas aeruginosa strains isolated in the Hospital Universitário São Francisco, Bragança Paulista, São Paulo, Brasil, was evaluated by pulsed field gel electrophoresis (PFGE). A unique clone was detected among 5 of 7 isolates, suggesting that cross...

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Bibliographic Details
Published in:The Brazilian journal of infectious diseases 2004-08, Vol.8 (4), p.267-271
Main Authors: Gales, Ana C, Torres, Patrícia L, Vilarinho, Dominique S O, Melo, Renata S, Silva, Claudinéia F L, Cereda, Rosângela F
Format: Article
Language:English
Subjects:
Adult
Aged
Anti-Bacterial Agents - pharmacology
Brazil - epidemiology
carbapenem
Carbapenems - pharmacology
Cross Infection - epidemiology
Cross Infection - microbiology
Disease Outbreaks
Drug Resistance, Bacterial - genetics
Electrophoresis, Gel, Pulsed-Field
Female
Genotype
Hospital Bed Capacity, 100 to 299
Hospitals, Teaching
Humans
INFECTIOUS DISEASES
Intensive Care Units
Male
Microbial Sensitivity Tests
Middle Aged
PFGE
Pseudomonas aeruginosa
Pseudomonas aeruginosa - drug effects
Pseudomonas aeruginosa - genetics
Pseudomonas Infections - epidemiology
Pseudomonas Infections - microbiology
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Summary:The genetic similarity of carbapenem-resistant Pseudomonas aeruginosa strains isolated in the Hospital Universitário São Francisco, Bragança Paulista, São Paulo, Brasil, was evaluated by pulsed field gel electrophoresis (PFGE). A unique clone was detected among 5 of 7 isolates, suggesting that cross-contamination might have played a role in the spread of carbapenem-resistant P. aeruginosa strains. Interestingly, a similar PFGE pattern was encountered in a P. aeruginosa strain isolated from Hospital São Paulo that was used as a PFGE control.
ISSN:1413-8670
1678-4391
1413-8670
DOI:10.1590/S1413-86702004000400001