Is the ≥1 cm Width of the Resection Margin in Benign and Borderline Phyllodes Tumor Necessary to Reduce Recurrence?

Background . Phyllodes tumors (PTs) are fibroepithelial neoplasms of the breast, with current treatment guidelines recommending wide excision to achieve surgical margins of ≥1 cm to minimize the recurrence risk. However, diagnostic challenges with core biopsy specimens often result in suboptimal sur...

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Bibliographic Details
Published in:The breast journal 2024-01, Vol.2024 (1)
Main Authors: Changchit, Nattakarn, Laokulrath, Natthawadee, Rushatamukayanunt, Pradit, Pisarnturakit, Pongthep
Format: Article
Language:English
Subjects:
Benign
Biopsy
Breast surgery
Decision making
Mastectomy
Multivariate analysis
Neoplasms
Patients
Tumors
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Summary:Background . Phyllodes tumors (PTs) are fibroepithelial neoplasms of the breast, with current treatment guidelines recommending wide excision to achieve surgical margins of ≥1 cm to minimize the recurrence risk. However, diagnostic challenges with core biopsy specimens often result in suboptimal surgical margins. This study aims to elucidate the correlation between margin status and PT recurrence, thereby informing surgical decision‐making and enhancing patient outcomes. Methods . This single‐center, retrospective study reviewed records of Thai women diagnosed with PTs between 2011 and 2018, collecting data on demographics, clinical presentation, surgical approach, tumor grade, size, and margin status. The primary endpoint was recurrence. Results . Among 165 PT cases analyzed—49.1% borderline, 38.2% benign, and 12.7% malignant—the overall recurrence rate was 13.9% ( n = 23) over a median follow‐up of 4.5 years. No significant difference in recurrence rates was observed between patients with negative resection margins
ISSN:1075-122X
1524-4741
DOI:10.1155/2024/1432313