Recent Advances on Iron(III) Selective Fluorescent Probes with Possible Applications in Bioimaging

Iron(III) is well-known to play a vital role in a variety of metabolic processes in almost all living systems, including the human body. However, the excess or deficiency of Fe from the normal permissible limit can cause serious health problems. Therefore, novel analytical methods are developed for...

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Bibliographic Details
Published in:Molecules (Basel, Switzerland) Switzerland), 2019-09, Vol.24 (18), p.3267
Main Authors: Sahoo, Suban K, Crisponi, Guido
Format: Article
Language:English
Subjects:
Analytical methods
Animals
Bioimaging
Biological properties
Biological samples
Biosensing Techniques
Cytotoxicity
Fibroblasts
Fluorescence
Fluorescent Dyes - chemistry
Fluorescent indicators
Fluorescent sensors
Health problems
Humans
Iron
Iron - chemistry
iron(III)
Medical imaging
Molecular Imaging - methods
Molecular Structure
Permeability
Probes
Ratiometric sensor
Response time
Review
Selectivity
Turn-on sensors
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Summary:Iron(III) is well-known to play a vital role in a variety of metabolic processes in almost all living systems, including the human body. However, the excess or deficiency of Fe from the normal permissible limit can cause serious health problems. Therefore, novel analytical methods are developed for the simple, direct, and cost-effective monitoring of Fe concentration in various environmental and biological samples. Because of the high selectivity and sensitivity, fast response time, and simplicity, the fluorescent-based molecular probes have been developed extensively in the past few decades to detect Fe . This review was narrated to summarize the Fe -selective fluorescent probes that show fluorescence enhancement (turn-on) and ratiometric response. The Fe sensing ability, mechanisms along with the analytical novelties of recently reported 77 fluorescent probes are discussed.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules24183267