High Killips Class as a Predictor of New-onset Atrial Fibrillation Following Acute Myocardial Infarction： Systematic Review and Meta-analysis

Background： Recent observational studies have shown that patients with higher Killips score （〉Ⅰ） have higher risk of new-onset atrial fibrillation （NOAF） following acute myocardial infarction （AMI）, while others drew a neutral conclusion. The ultimate predictive value of high Killips class on NOAF r...

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Bibliographic Details
Published in:Chinese medical journal 2015-07, Vol.128 (14), p.1964-1968
Main Authors: Zhang, En-Yuan, Cui, Li, Li, Zhen-Yu, Liu, Tong, Li, Guang-Ping
Format: Article
Language:English
Subjects:
Acute Myocardial Infarction
Killips
AMI
Analysis
Atrial fibrillation
Atrial Fibrillation - diagnosis
Atrial Fibrillation - etiology
Biological markers
Cardiac arrhythmia
Cardiology
Cardiovascular disease
Electrocardiography
Heart attack
Heart attacks
Heart failure
Hospitals
Humans
Laboratories
Meta Analysis
Multivariate analysis
Myocardial Infarction - complications
New-onset Atrial Fibrillation
Prognosis
Risk Factors
Studies
凯利
急性心肌梗死
房颤
模糊
系统
预测值
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Summary:Background： Recent observational studies have shown that patients with higher Killips score （〉Ⅰ） have higher risk of new-onset atrial fibrillation （NOAF） following acute myocardial infarction （AMI）, while others drew a neutral conclusion. The ultimate predictive value of high Killips class on NOAF remained obscure. Methods： PubMed, Web of Science, China National Knowledge Infrastructure, and the Cochrane Controlled Trials Register Databases were searched until February 2015. Of the 3732 initially identified studies, 5 observational studies with 10,053 patients were analyzed. Results： The meta-analysis of these studies showed that higher Killips score on admission was associated with higher incidence of NOAF following AMI （odds ratio 2.29, 95% confidence intcrwd 1.96 2.67, P 〈 0.00001 ）, while no significant differences exist among individual trials （P =0.14 and I^2= 43%）. Conclusions： Killips class 〉I was associated with the higher opportunity of developing NOAF following AMI.
ISSN:0366-6999
2542-5641
DOI:10.4103/0366-6999.160565