Sites of metastasis and overall survival in esophageal cancer: a population-based study

There are few population-based studies of the sites of distant metastasis (DM) and survival from esophageal cancer (EC). The aim of this study was to assess the patterns and survival outcomes for site-specific DM from EC using a population-based approach. Patients diagnosed with de novo stage IV EC...

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Bibliographic Details
Published in:Cancer management and research 2017-01, Vol.9, p.781-788
Main Authors: Wu, San-Gang, Zhang, Wen-Wen, He, Zhen-Yu, Sun, Jia-Yuan, Chen, Yong-Xiong, Guo, Ling
Format: Article
Language:English
Subjects:
bone metastases
Brain cancer
brain metastases
Breast cancer
Cancer metastasis
Cancer therapies
Care and treatment
Chemotherapy
Classification
Collaboration
Confidence intervals
Development and progression
Epidemiology
Esophageal cancer
Ethnicity
Health aspects
Health risk assessment
Hospitals
Kidney cancer
Laboratories
Liver
liver metastases
Lung cancer
lung metastases
Lymphatic system
Medical prognosis
Metastasis
Oncology
Original Research
Patients
Physiological aspects
Population
Population-based studies
Quality of life
Radiation therapy
SEER
Surgery
Systematic review
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Summary:There are few population-based studies of the sites of distant metastasis (DM) and survival from esophageal cancer (EC). The aim of this study was to assess the patterns and survival outcomes for site-specific DM from EC using a population-based approach. Patients diagnosed with de novo stage IV EC between 2010 and 2014 were identified from the Surveillance, Epidemiology, and End Results program database. Overall survival (OS) was compared according to the site of DM. We included 3218 patients in this study; the most common site of DM was the liver, followed by distant lymph nodes, lung, bone and brain. Median OS for patients with liver, distant lymph node, lung, bone, and brain metastases was 5, 10, 6, 4, and 6 months, respectively (
ISSN:1179-1322
1179-1322
DOI:10.2147/CMAR.S150350