Malignant and Noninvasive Skin Tumours in Renal Transplant Recipients

Transplant recipients require immunosuppression to prevent graft rejection. This conveys an increased risk of malignancy, particularly skin tumours. There is a need for up-to-date data for the South of England. Method. Pathology records were reviewed for 709 kidney transplant recipients on immunosup...

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Bibliographic Details
Published in:Dermatology Research and Practice 2014-01, Vol.2014 (2014), p.67-72
Main Authors: Popoola, Joyce, Quante, Mara, Williams, Sion K., Dobson, Joelle S., Roche, Christopher D., Chow, Jade W. M.
Format: Article
Language:English
Subjects:
Diagnosis
Health aspects
Immunotherapy
Kidneys
Melanoma
Organ transplant recipients
Prevention
Transplantation
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Summary:Transplant recipients require immunosuppression to prevent graft rejection. This conveys an increased risk of malignancy, particularly skin tumours. There is a need for up-to-date data for the South of England. Method. Pathology records were reviewed for 709 kidney transplant recipients on immunosuppression at our hospital from 1995 to 2008. Skin tumours were recorded/analysed. Results. Mean age at transplant was 46 years. Mean length of follow-up was 7.2 years and total follow-up was 4926 person-years. 53 (7.5%) patients (39/458 (8.5%) males and 14/251 (5.6%) females) developed ≥1 skin malignancy. Cumulative incidences of 4.0%, 7.5%, and 12.2% were observed for those with
ISSN:1687-6105
1687-6113
DOI:10.1155/2014/409058