Natural polymer‐based adhesive hydrogel for biomedical applications

Hydrogel is a polymer network system that can form a hydrophilic three‐dimensional network structure through different cross‐linking methods. In recent years, hydrogels have received considerable attention due to their good biocompatibility and biodegradability by introducing different cross‐linking...

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Bibliographic Details
Published in:Biosurface and biotribology 2022-06, Vol.8 (2), p.69-94
Main Authors: Long, Siyu, Xie, Chaoming, Lu, Xiong
Format: Article
Language:English
Subjects:
Adhesion
Adhesives
Amino acids
Biocompatibility
biomedical applications
Body fluids
Bond strength
Cartilage
Chemical bonds
Chemistry
design principles
Hydrocarbons
Hydrogels
Hydrogen bonds
Mechanical properties
Mollusks
natural polymer‐based adhesive hydrogels
Polymers
Proteins
tissue adhesion
Water
Wound healing
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Summary:Hydrogel is a polymer network system that can form a hydrophilic three‐dimensional network structure through different cross‐linking methods. In recent years, hydrogels have received considerable attention due to their good biocompatibility and biodegradability by introducing different cross‐linking mechanisms and functional components. Compared with synthetic hydrogels, natural polymer‐based hydrogels have low biotoxicity, high cell affinity, and great potential for biomedical fields; however, their mechanical properties and tissue adhesion capabilities have been unable to meet clinical requirements. In recent years, many efforts have been made to solve these issues. In this review, the recent progress in the field of natural polymer‐based adhesive hydrogels is highlighted. The authors first introduce the general design principles for the natural polymer‐based adhesive hydrogels being used as excellent tissue adhesives and the challenges associated with their design. Next, their usages in biomedical applications are summarised, such as wound healing, haemostasis, nerve repair, bone tissue repair, cartilage tissue repair, electronic devices, and other tissue repairs. Finally, the potential challenges of natural polymer‐based adhesive hydrogels are presented.
ISSN:2405-4518
2405-4518
DOI:10.1049/bsb2.12036