Yttrium-90 radioembolization in desmoplastic small round cell tumor with recurrent hepatic metastasis following hyperthermic intraperitoneal chemotherapy

We report a case of a 26-year-old male who was diagnosed with metastatic desmoplastic small round cell tumor initially treated with systemic chemotherapy followed by tumor debulking and hyperthermic intra-peritoneal chemotherapy. The patient was in complete remission by clinical and imaging criteria...

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Bibliographic Details
Published in:Radiology case reports 2021-06, Vol.16 (6), p.1259-1263
Main Authors: Gill, Harkanwar, Shahbazi, Natalie, Yu, Zhongxin, Vanlandingham, William
Format: Article
Language:English
Subjects:
Case Report
Desmoplastic tumor
Hepatic metastasis
Radioembolization
Yttrium 90
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Summary:We report a case of a 26-year-old male who was diagnosed with metastatic desmoplastic small round cell tumor initially treated with systemic chemotherapy followed by tumor debulking and hyperthermic intra-peritoneal chemotherapy. The patient was in complete remission by clinical and imaging criteria for 11 months, until he developed bi-lobar hepatic disease, which was successfully treated with selective internal radiation therapy by Yttrium-90. The patient demonstrated liver-specific complete response on follow-up imaging obtained 18 months after the procedure.
ISSN:1930-0433
1930-0433
DOI:10.1016/j.radcr.2021.02.066