Synthesis of novel rhodanine based functionalized furans from the reaction of tert-butyl isocyanide with acetylenic esters in the presence of rhodanine acetic acid derivatives

The reactive 1:1 intermediate produced from the reaction of tert-butyl isocyanide and dialkyl acetylenedicarboxylates was trapped by rhodanine-N-acetic acid derivatives to generate polyfunctionalized furan rings in fairly good yields. The reactive 1:1 intermediate produced from the reaction of tert-...

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Bibliographic Details
Published in:Arabian journal of chemistry 2019-11, Vol.12 (7), p.1496-1500
Main Authors: Baharfar, Robabeh, Asghari, Sakineh, Peiman, Sahar
Format: Article
Language:English
Subjects:
Dialkyl acetylenedicarboxylate
Multi-component reaction
Rhodanine-N-acetic acid
tert-Butyl isocyanide
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Summary:The reactive 1:1 intermediate produced from the reaction of tert-butyl isocyanide and dialkyl acetylenedicarboxylates was trapped by rhodanine-N-acetic acid derivatives to generate polyfunctionalized furan rings in fairly good yields. The reactive 1:1 intermediate produced from the reaction of tert-butyl isocyanide and dialkyl acetylenedicarboxylates was trapped by rhodanine-N-acetic acid derivatives to generate polyfunctionalized furan rings in fairly good yields.
ISSN:1878-5352
1878-5379
DOI:10.1016/j.arabjc.2014.10.030