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Comparison of survival and perioperative outcomes following simple and radical hysterectomy for stage II endometrial cancer: a single-institution, retrospective, matched-pair analysis
Objective We aimed to compare the survival and perioperative outcomes of patients with stage II endometrial cancer (EC) undergoing simple hysterectomy (SH) or radical hysterectomy (RH), to validate the various guidelines. Methods A total of 155 consecutive patients diagnosed with stage II EC from 20...
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| Published in: | Journal of international medical research 2019-09, Vol.47 (9), p.4469-4481 |
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| Main Authors: | , , , , , , |
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| cites | cdi_FETCH-LOGICAL-c528t-557294379cf3a55309f315ffd9b2b15e9e816b06ba4f2526e4c461234b8496133 |
| container_end_page | 4481 |
| container_issue | 9 |
| container_start_page | 4469 |
| container_title | Journal of international medical research |
| container_volume | 47 |
| creator | Jiang, Yahui Jia, Nan Zhu, Menghan He, Yuan Che, Xiaoxia Lv, Tianjiao Feng, Weiwei |
| description | Objective
We aimed to compare the survival and perioperative outcomes of patients with stage II endometrial cancer (EC) undergoing simple hysterectomy (SH) or radical hysterectomy (RH), to validate the various guidelines.
Methods
A total of 155 consecutive patients diagnosed with stage II EC from 2000 to 2014 were reviewed. We identified 40 pairs of patients (40 SH and 40 RH) who were matched in terms of age, pathological type, and lymphovascular space invasion status using matched-pair analysis. Patient data were collected from medical records and outcomes were determined by telephone follow-up.
Results
Among the 80 patients in the two groups, seven died from tumor recurrence. However, cancer-related survival rates were not significantly different between the SH and RH groups. The 3-year cancer-related survival rates in the SH and RH groups were 94.97% and 92.53%, and the 5-year survival rates were 92.40% and 90.03%, respectively. Regarding perioperative outcomes, the SH group had significantly less intraoperative bleeding and a significantly shorter catheter-indwelling time than the RH group.
Conclusions
SH provides similar survival outcomes and a superior perioperative quality of life compared with RH in patients with stage II EC. |
| doi_str_mv | 10.1177/0300060519863190 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_f7a7de70302242858d28ec5dfe20cbb6</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_0300060519863190</sage_id><doaj_id>oai_doaj_org_article_f7a7de70302242858d28ec5dfe20cbb6</doaj_id><sourcerecordid>2267019932</sourcerecordid><originalsourceid>FETCH-LOGICAL-c528t-557294379cf3a55309f315ffd9b2b15e9e816b06ba4f2526e4c461234b8496133</originalsourceid><addsrcrecordid>eNp1kktv1DAQgCMEoqVw54QsceHQgB-x43CohFY8VqrEBc6W44x3vXLiYDuL9pfx9_B2S6GVuNiS55tv7PFU1UuC3xLStu8wwxgLzEknBSMdflSdk6ZlNS3nj6vzY7g-xs-qZyntMG6o4PRpdcYI462U9Lz6tQrjrKNLYULBorTEvdtrj_Q0oBmiC2XR2e0BhSWbMEJCNngffrppg5IbZw83bNSDMyVve0gZIpgcxkMhI0pZbwCt1wimoaTn6Apl9GQgvke6KKaNh9pNKbu8ZBemSxQLFdJcJKXuJRp1NlsY6lm7WGppf0guPa-eWO0TvLjdL6rvnz5-W32pr79-Xq8-XNeGU5lrzlvaNaztjGWac4Y7ywi3duh62hMOHUgieix63VjKqYDGNIJQ1vSy6QRh7KJan7xD0Ds1RzfqeFBBO3VzEOJG6Zid8aBsq9sB2tJ0ShsquRyoBMMHCxSbvhfFdXVyzUs_wmBgylH7e9L7kclt1SbslWg54-IoeHMriOHHAimr0SUD3usJwpIUpaLFpOsYLejrB-guLLE0r1CMMS6lFLhQ-ESZ0vAUwd5dhmB1nDD1cMJKyqt_H3GX8GekClCfgFQ-_m_V_wp_A5173Kc</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2333588860</pqid></control><display><type>article</type><title>Comparison of survival and perioperative outcomes following simple and radical hysterectomy for stage II endometrial cancer: a single-institution, retrospective, matched-pair analysis</title><source>SAGE Open Access</source><source>Publicly Available Content Database</source><source>PubMed Central</source><creator>Jiang, Yahui ; Jia, Nan ; Zhu, Menghan ; He, Yuan ; Che, Xiaoxia ; Lv, Tianjiao ; Feng, Weiwei</creator><creatorcontrib>Jiang, Yahui ; Jia, Nan ; Zhu, Menghan ; He, Yuan ; Che, Xiaoxia ; Lv, Tianjiao ; Feng, Weiwei</creatorcontrib><description>Objective
We aimed to compare the survival and perioperative outcomes of patients with stage II endometrial cancer (EC) undergoing simple hysterectomy (SH) or radical hysterectomy (RH), to validate the various guidelines.
Methods
A total of 155 consecutive patients diagnosed with stage II EC from 2000 to 2014 were reviewed. We identified 40 pairs of patients (40 SH and 40 RH) who were matched in terms of age, pathological type, and lymphovascular space invasion status using matched-pair analysis. Patient data were collected from medical records and outcomes were determined by telephone follow-up.
Results
Among the 80 patients in the two groups, seven died from tumor recurrence. However, cancer-related survival rates were not significantly different between the SH and RH groups. The 3-year cancer-related survival rates in the SH and RH groups were 94.97% and 92.53%, and the 5-year survival rates were 92.40% and 90.03%, respectively. Regarding perioperative outcomes, the SH group had significantly less intraoperative bleeding and a significantly shorter catheter-indwelling time than the RH group.
Conclusions
SH provides similar survival outcomes and a superior perioperative quality of life compared with RH in patients with stage II EC.</description><identifier>ISSN: 0300-0605</identifier><identifier>EISSN: 1473-2300</identifier><identifier>DOI: 10.1177/0300060519863190</identifier><identifier>PMID: 31357882</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Adult ; Aged ; Clinical Research Reports ; Endometrial cancer ; Endometrial Neoplasms - pathology ; Endometrial Neoplasms - surgery ; Female ; Humans ; Hysterectomy ; Matched-Pair Analysis ; Middle Aged ; Multivariate Analysis ; Neoplasm Staging ; Perioperative Care ; Prognosis ; Retrospective Studies ; Survival Analysis ; Young Adult</subject><ispartof>Journal of international medical research, 2019-09, Vol.47 (9), p.4469-4481</ispartof><rights>The Author(s) 2019</rights><rights>The Author(s) 2019. This work is licensed under the Creative Commons Attribution – Non-Commercial License http://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2019 2019 SAGE Publications</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c528t-557294379cf3a55309f315ffd9b2b15e9e816b06ba4f2526e4c461234b8496133</citedby><cites>FETCH-LOGICAL-c528t-557294379cf3a55309f315ffd9b2b15e9e816b06ba4f2526e4c461234b8496133</cites><orcidid>0000-0002-2120-0525 ; 0000-0002-2923-1713</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753566/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2333588860?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,882,21947,25734,27834,27905,27906,36993,36994,44571,44926,45314,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31357882$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jiang, Yahui</creatorcontrib><creatorcontrib>Jia, Nan</creatorcontrib><creatorcontrib>Zhu, Menghan</creatorcontrib><creatorcontrib>He, Yuan</creatorcontrib><creatorcontrib>Che, Xiaoxia</creatorcontrib><creatorcontrib>Lv, Tianjiao</creatorcontrib><creatorcontrib>Feng, Weiwei</creatorcontrib><title>Comparison of survival and perioperative outcomes following simple and radical hysterectomy for stage II endometrial cancer: a single-institution, retrospective, matched-pair analysis</title><title>Journal of international medical research</title><addtitle>J Int Med Res</addtitle><description>Objective
We aimed to compare the survival and perioperative outcomes of patients with stage II endometrial cancer (EC) undergoing simple hysterectomy (SH) or radical hysterectomy (RH), to validate the various guidelines.
Methods
A total of 155 consecutive patients diagnosed with stage II EC from 2000 to 2014 were reviewed. We identified 40 pairs of patients (40 SH and 40 RH) who were matched in terms of age, pathological type, and lymphovascular space invasion status using matched-pair analysis. Patient data were collected from medical records and outcomes were determined by telephone follow-up.
Results
Among the 80 patients in the two groups, seven died from tumor recurrence. However, cancer-related survival rates were not significantly different between the SH and RH groups. The 3-year cancer-related survival rates in the SH and RH groups were 94.97% and 92.53%, and the 5-year survival rates were 92.40% and 90.03%, respectively. Regarding perioperative outcomes, the SH group had significantly less intraoperative bleeding and a significantly shorter catheter-indwelling time than the RH group.
Conclusions
SH provides similar survival outcomes and a superior perioperative quality of life compared with RH in patients with stage II EC.</description><subject>Adult</subject><subject>Aged</subject><subject>Clinical Research Reports</subject><subject>Endometrial cancer</subject><subject>Endometrial Neoplasms - pathology</subject><subject>Endometrial Neoplasms - surgery</subject><subject>Female</subject><subject>Humans</subject><subject>Hysterectomy</subject><subject>Matched-Pair Analysis</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Neoplasm Staging</subject><subject>Perioperative Care</subject><subject>Prognosis</subject><subject>Retrospective Studies</subject><subject>Survival Analysis</subject><subject>Young Adult</subject><issn>0300-0605</issn><issn>1473-2300</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>AFRWT</sourceid><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNp1kktv1DAQgCMEoqVw54QsceHQgB-x43CohFY8VqrEBc6W44x3vXLiYDuL9pfx9_B2S6GVuNiS55tv7PFU1UuC3xLStu8wwxgLzEknBSMdflSdk6ZlNS3nj6vzY7g-xs-qZyntMG6o4PRpdcYI462U9Lz6tQrjrKNLYULBorTEvdtrj_Q0oBmiC2XR2e0BhSWbMEJCNngffrppg5IbZw83bNSDMyVve0gZIpgcxkMhI0pZbwCt1wimoaTn6Apl9GQgvke6KKaNh9pNKbu8ZBemSxQLFdJcJKXuJRp1NlsY6lm7WGppf0guPa-eWO0TvLjdL6rvnz5-W32pr79-Xq8-XNeGU5lrzlvaNaztjGWac4Y7ywi3duh62hMOHUgieix63VjKqYDGNIJQ1vSy6QRh7KJan7xD0Ds1RzfqeFBBO3VzEOJG6Zid8aBsq9sB2tJ0ShsquRyoBMMHCxSbvhfFdXVyzUs_wmBgylH7e9L7kclt1SbslWg54-IoeHMriOHHAimr0SUD3usJwpIUpaLFpOsYLejrB-guLLE0r1CMMS6lFLhQ-ESZ0vAUwd5dhmB1nDD1cMJKyqt_H3GX8GekClCfgFQ-_m_V_wp_A5173Kc</recordid><startdate>20190901</startdate><enddate>20190901</enddate><creator>Jiang, Yahui</creator><creator>Jia, Nan</creator><creator>Zhu, Menghan</creator><creator>He, Yuan</creator><creator>Che, Xiaoxia</creator><creator>Lv, Tianjiao</creator><creator>Feng, Weiwei</creator><general>SAGE Publications</general><general>Sage Publications Ltd</general><general>SAGE Publishing</general><scope>AFRWT</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-2120-0525</orcidid><orcidid>https://orcid.org/0000-0002-2923-1713</orcidid></search><sort><creationdate>20190901</creationdate><title>Comparison of survival and perioperative outcomes following simple and radical hysterectomy for stage II endometrial cancer: a single-institution, retrospective, matched-pair analysis</title><author>Jiang, Yahui ; Jia, Nan ; Zhu, Menghan ; He, Yuan ; Che, Xiaoxia ; Lv, Tianjiao ; Feng, Weiwei</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c528t-557294379cf3a55309f315ffd9b2b15e9e816b06ba4f2526e4c461234b8496133</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Clinical Research Reports</topic><topic>Endometrial cancer</topic><topic>Endometrial Neoplasms - pathology</topic><topic>Endometrial Neoplasms - surgery</topic><topic>Female</topic><topic>Humans</topic><topic>Hysterectomy</topic><topic>Matched-Pair Analysis</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Neoplasm Staging</topic><topic>Perioperative Care</topic><topic>Prognosis</topic><topic>Retrospective Studies</topic><topic>Survival Analysis</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jiang, Yahui</creatorcontrib><creatorcontrib>Jia, Nan</creatorcontrib><creatorcontrib>Zhu, Menghan</creatorcontrib><creatorcontrib>He, Yuan</creatorcontrib><creatorcontrib>Che, Xiaoxia</creatorcontrib><creatorcontrib>Lv, Tianjiao</creatorcontrib><creatorcontrib>Feng, Weiwei</creatorcontrib><collection>SAGE Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Complete (ProQuest Database)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Directory of Open Access Journals</collection><jtitle>Journal of international medical research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jiang, Yahui</au><au>Jia, Nan</au><au>Zhu, Menghan</au><au>He, Yuan</au><au>Che, Xiaoxia</au><au>Lv, Tianjiao</au><au>Feng, Weiwei</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of survival and perioperative outcomes following simple and radical hysterectomy for stage II endometrial cancer: a single-institution, retrospective, matched-pair analysis</atitle><jtitle>Journal of international medical research</jtitle><addtitle>J Int Med Res</addtitle><date>2019-09-01</date><risdate>2019</risdate><volume>47</volume><issue>9</issue><spage>4469</spage><epage>4481</epage><pages>4469-4481</pages><issn>0300-0605</issn><eissn>1473-2300</eissn><abstract>Objective
We aimed to compare the survival and perioperative outcomes of patients with stage II endometrial cancer (EC) undergoing simple hysterectomy (SH) or radical hysterectomy (RH), to validate the various guidelines.
Methods
A total of 155 consecutive patients diagnosed with stage II EC from 2000 to 2014 were reviewed. We identified 40 pairs of patients (40 SH and 40 RH) who were matched in terms of age, pathological type, and lymphovascular space invasion status using matched-pair analysis. Patient data were collected from medical records and outcomes were determined by telephone follow-up.
Results
Among the 80 patients in the two groups, seven died from tumor recurrence. However, cancer-related survival rates were not significantly different between the SH and RH groups. The 3-year cancer-related survival rates in the SH and RH groups were 94.97% and 92.53%, and the 5-year survival rates were 92.40% and 90.03%, respectively. Regarding perioperative outcomes, the SH group had significantly less intraoperative bleeding and a significantly shorter catheter-indwelling time than the RH group.
Conclusions
SH provides similar survival outcomes and a superior perioperative quality of life compared with RH in patients with stage II EC.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>31357882</pmid><doi>10.1177/0300060519863190</doi><tpages>13</tpages><orcidid>https://orcid.org/0000-0002-2120-0525</orcidid><orcidid>https://orcid.org/0000-0002-2923-1713</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of international medical research, 2019-09, Vol.47 (9), p.4469-4481 |
| issn | 0300-0605 1473-2300 |
| language | eng |
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| source | SAGE Open Access; Publicly Available Content Database; PubMed Central |
| subjects | Adult Aged Clinical Research Reports Endometrial cancer Endometrial Neoplasms - pathology Endometrial Neoplasms - surgery Female Humans Hysterectomy Matched-Pair Analysis Middle Aged Multivariate Analysis Neoplasm Staging Perioperative Care Prognosis Retrospective Studies Survival Analysis Young Adult |
| title | Comparison of survival and perioperative outcomes following simple and radical hysterectomy for stage II endometrial cancer: a single-institution, retrospective, matched-pair analysis |
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