Partial agenesis of the dorsal pancreas with features of chronic pancreatitis: A case report

• Published in: Radiology case reports 2025-01, Vol.20 (1), p.674-679
• Main Authors: Foladi, Naqibullah, Farzam, Farhad, Milad Fekrat, Sayed Mohammad, Rahil, Najibullah, Karimy, Mohammad Javid
• Format: Article
• Language: English
• Subjects: Case Report; Dorsal pancreatic agenesis; Partial agenesis of the dorsal pancreas
• ISSN: 1930-0433; 1930-0433
• DOI: 10.1016/j.radcr.2024.10.050

Complete agenesis of the pancreas or the absence of its ventral portion is incompatible with life. However, agenesis of the dorsal pancreas is a relatively benign condition. Partial agenesis of the dorsal pancreas (ADP) arises from abnormal embryogenesis, although the exact etiology remains unknown. In cases of complete dorsal pancreas agenesis, the head, body, tail, minor duodenal papilla, and duct of Santorini are absent, while partial agenesis involves only the minor duodenal papilla and Santorini duct. We present the case of a 60-year-old woman with nonspecific abdominal pain, referred for an abdominal CT scan. The scan revealed the uncinate process and partial head of the pancreas, including the ducts of Wirsung and Santorini, while the remainder of the dorsal pancreas was absent. These findings are consistent with partial ADP. Additionally, multifocal dense calcifications were noted in the ventral pancreas, suggesting chronic pancreatitis. No associated anomalies or additional symptoms were detected. Partial ADP is a scarce condition, and the coexistence of chronic pancreatitis further contributes to its uniqueness. The etiology of chronic pancreatitis in this case remains unclear. The increasing recognition of ADP in recent years is likely due to advances in radiological imaging. Imaging plays a crucial role not only in diagnosing ADP but also in assessing prognosis and detecting any associated anomalies. While specific treatment is unnecessary in the absence of other anomalies, annual screening is recommended due to the potential risk of malignancy in the ventral pancreas.