Wilson’s Disease Presenting with Generalized Tonic-Clonic Seizure and Cerebellar Dysfunction

Wilson's disease (WD) is a rare inherited impaired copper metabolism with diverse clinical pictures dominated by hepatic and neurologic manifestations. We report the case of a 14-year-old female patient who attended the Department of Neuropsychiatry at Ali Abad Teaching Hospital, Kabul, Afghani...

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Bibliographic Details
Published in:International medical case reports journal 2021-08, Vol.14, p.529-532
Main Authors: Rasib, Aziz Rahman, Jabarkhil, Aemal Aziz, Sediqi, Mohammad Faiq, Mansoor, Ahmad Irshad, Asady, Abdullah
Format: Article
Language:English
Subjects:
Asymptomatic
Ataxia
Brain
Case Report
Case reports
cerebellar dysfunction
Convulsions & seizures
copper accumulation
Disease
Drug therapy
Dysarthria
Dystonia
Encephalitis
Epilepsy
Gait
Health aspects
Hepatitis
Injuries
kf rings
Levetiracetam
Liver
Magnetic resonance imaging
Metabolism
Movement disorders
Mutation
Patients
Physiological aspects
seizure
Tremor (Muscular contraction)
Trientine
Ultrasonic imaging
wilson’s disease
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Summary:Wilson's disease (WD) is a rare inherited impaired copper metabolism with diverse clinical pictures dominated by hepatic and neurologic manifestations. We report the case of a 14-year-old female patient who attended the Department of Neuropsychiatry at Ali Abad Teaching Hospital, Kabul, Afghanistan, with generalized tonic-clonic seizure and cerebellar dysfunction. The patient was initially diagnosed as encephalitis and epilepsy and finally diagnosed with WD based on the clinical and laboratory findings. After 6 months of follow-up, the patient showed substantial clinical recovery. Keywords: Wilson's disease, copper accumulation, KF rings, seizure, cerebellar dysfunction
ISSN:1179-142X
1179-142X
DOI:10.2147/IMCRJ.S320639