Developmental origin of tendon diversity in Drosophila melanogaster

Myogenesis is a developmental process that is largely conserved in both and higher organisms. Consequently, the fruit fly is an excellent model for identifying the genes and mechanisms involved in muscle development. Moreover, there is growing evidence indicating that specific conserved genes and si...

Full description

Saved in:
Bibliographic Details
Published in:Frontiers in physiology 2023-04, Vol.14, p.1176148-1176148
Main Authors: Moucaud, Blandine, Prince, Elodie, Jagla, Krzysztof, Soler, Cédric
Format: Article
Language:English
Subjects:
development
Drosophila
muscle
myogenesis
Physiology
tendon
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Myogenesis is a developmental process that is largely conserved in both and higher organisms. Consequently, the fruit fly is an excellent model for identifying the genes and mechanisms involved in muscle development. Moreover, there is growing evidence indicating that specific conserved genes and signaling pathways govern the formation of tissues that connect the muscles to the skeleton. In this review, we present an overview of the different stages of tendon development, from the specification of tendon progenitors to the assembly of a stable myotendinous junction across three different myogenic contexts in : larval, flight and leg muscle development. We underline the different aspects of tendon cell specification and differentiation in embryo and during metamorphosis that result into tendon morphological and functional diversity.
ISSN:1664-042X
1664-042X
DOI:10.3389/fphys.2023.1176148