Comment on Yeste et al. Polyphenols and IUGR Pregnancies: Intrauterine Growth Restriction and Hydroxytyrosol Affect the Development and Neurotransmitter Profile of the Hippocampus in a Pig Model. Antioxidants 2021, 10 , 1505

Intrauterine growth restriction (IUGR) affects 5-10% of newborns and increases the risks of intrauterine demise, neonatal morbidity, and death. In their recent publication, Yeste et al. found the benefits of hydroxytyrosol supplementation on brain remodeling from an IUGR pig model. Additionally, we...

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Published in:Antioxidants 2022-04, Vol.11 (5), p.833
Main Authors: Garrabou, Glòria, Hernández, Ana Sandra, Guitart-Mampel, Mariona, Escalada-Casellas, Elena, Malats-Revelles, Gemma, Castro-Barquero, Sara, Ruiz-León, Ana María, Vellvé, Kilian, Casas, Rosa, Cardellach, Francesc, Crispi, Fàtima, García-García, Francesc Josep
Format: Article
Language:English
Subjects:
Adults
Antioxidants
balanced diet
Biomarkers
Cardiovascular disease
Comment
Diet
Dietary supplements
Fetuses
Food
Gestational age
Hogs
hydroxytyrosol
intrauterine growth restriction
Mediterranean diet
Morbidity
Neonates
Oxidative stress
Phenolic compounds
Polyphenols
Pregnancy
supplementation
Tyrosol
Vitamins
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Summary:Intrauterine growth restriction (IUGR) affects 5-10% of newborns and increases the risks of intrauterine demise, neonatal morbidity, and death. In their recent publication, Yeste et al. found the benefits of hydroxytyrosol supplementation on brain remodeling from an IUGR pig model. Additionally, we found a significant decrease in phenolic alcohol (tyrosol and hydroxytyrosol) intake in IUGR pregnant women. Altogether, these findings support the notion that dietetic interventions, through supplementation but mostly via a balanced diet, can ameliorate IUGR complications. Furthermore, diet intervention combined with early biomarkers may allow clinicians to eventually anticipate IUGR diagnosis and help avoid one of the most frequent causes of newborn mortality and morbidity.
ISSN:2076-3921
2076-3921
DOI:10.3390/antiox11050833