An Unusual Case of Adrenocortical Carcinoma with Multiple Facets

Adrenocortical carcinoma (ACC) is a rare malignant tumour from the adrenal cortex. Half of the cases are functional, with ACTH-independent autonomous cortisol production being the most common. It is rare for ACC to present with markedly elevated metanephrine levels, characteristic of pheochromocytom...

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Bibliographic Details
Published in:Journal of the ASEAN Federation of Endocrine Societies 2024-01, Vol.39 (2), p.92-96
Main Authors: Tan, Jie En, Tan, Florence Hui Sieng, Kuan, Yueh Chien, Chan, Pei Lin, Yusri, Yusuf
Format: Article
Language:English
Subjects:
adrenocortical carcinoma
Case Report
pheochromocytoma
urine fractionated metanephrines
Online Access:Get full text
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Summary:Adrenocortical carcinoma (ACC) is a rare malignant tumour from the adrenal cortex. Half of the cases are functional, with ACTH-independent autonomous cortisol production being the most common. It is rare for ACC to present with markedly elevated metanephrine levels, characteristic of pheochromocytoma. We report a case of a large functioning adrenal tumour with overlapping biochemical features of ACC and pheochromocytoma. Biopsy confirmed the histopathological diagnosis of metastatic ACC.
ISSN:0857-1074
2308-118X
DOI:10.15605/jafes.039.02.16