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The course and out-come of a pregnancy superimposing untreated Graves' thyrotoxicosis

Objective: The objective of this case report is to highlight the occurrence of a pregnancy in an African woman with untreated Graves' thyrotoxicosis; there being a virtual absence in the literature of reports about similar observations in humans. Case report: Described here is one case of a pre...

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Bibliographic Details
Published in:International Journal of Medicine and Health Development 2001-01, Vol.6 (1), p.51-52
Main Authors: A U Mbah, J M Okaro
Format: Article
Language:English
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Summary:Objective: The objective of this case report is to highlight the occurrence of a pregnancy in an African woman with untreated Graves' thyrotoxicosis; there being a virtual absence in the literature of reports about similar observations in humans. Case report: Described here is one case of a pregnancy that occurred in a Nigerian woman with unrecognized Graves' thyrotoxicosis. The pregnancy was carried until the 25th week before thyrotoxicosis was correctly diagnosed and antithyroid therapy instituted. Aspects of the course and out-come of the pregnancy relevant to the current understanding of the relationship between maternal thyroid hyper function and foetal development are discussed. Conclusion: It is concluded that the mechanisms involved in the adverse foetal developmental effects of thyrotoxicosis in pregnancy are complex and yet to be fully understood.
ISSN:2635-3695