Sphingolipids of plant pathogenic fungi

Glycosphingolipids in filamentous fungi are significant components of the plasma membrane and are vital for different cellular processes, such as growth, morphological transition or signal transduction. Fungal growth inhibitors targeting glycosylinositolphosphoceramide (GIPCs) biosynthesis or antifu...

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Bibliographic Details
Published in:Plant protection science 2021-01, Vol.57 (2), p.134-139
Main Authors: Gharwalová, Lucia, Kulišová, Markéta, Vasyliuk, Anastasiia, Marešová, Helena, Palyzová, Andrea, Nedbalová, Linda, Kolouchová, Irena
Format: Article
Language:English
Subjects:
Biosynthesis
Carbohydrates
defensin
Defensins
filamentous fungi
Fungi
Fungicides
Glycosphingolipids
glycosylinositolphosphoceramides
high resolution tandem electrospray mass spectrometry
Inositol
Mammalian cells
Mass spectrometry
Mass spectroscopy
Membranes
Saccharides
Shotguns
Signal processing
Signal transduction
Sphingolipids
vitis vinifera
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Summary:Glycosphingolipids in filamentous fungi are significant components of the plasma membrane and are vital for different cellular processes, such as growth, morphological transition or signal transduction. Fungal growth inhibitors targeting glycosylinositolphosphoceramide (GIPCs) biosynthesis or antifungal compounds binding to GIPCs present in membranes could present a safe way of preventing fungal growth on crops since GIPCs are not present in mammalian cells. Mass spectrometry-based shotgun lipidomics was used to analyze sphingolipids of 11 fungal strains isolated from plant material. Molecular species with inositol ceramides containing zero to five carbohydrates were identified. Differences in the amount of individual molecular species were influenced by the taxonomic affiliation. All tested strains exhibited a relatively high content (more than 40 mol.%) of GIPCs with three and more saccharides attached to the polar head. It could be assumed that the sphingolipid profiles of the tested plant pathogens would be an adaptation mechanism to antifungal plant defensins.
ISSN:1212-2580
1805-9341
DOI:10.17221/131/2020-PPS