Risperidone-Induced Neutropenia in a Schizophrenic Patient: A Case Report and Literature Review

Neutropenia is an adverse effect of various pharmacological therapies, including antipsychotics. Among the second-generation antipsychotic (SGA) medications, clozapine is most notable for neutropenic adverse effect. Risperidone, another SGA drug, is linked mainly with metabolic adverse effects, but...

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Bibliographic Details
Published in:Case reports in psychiatry 2021-08, Vol.2021, p.1-3
Main Authors: Atolagbe, Ayodele, Nkemjika, Stanley, Popoola, Olusegun, Oladeji, Oluwatoyin, Kogan, Irina, Saeed, Haroon, Olupona, Tolulope
Format: Article
Language:English
Subjects:
African American women
Antipsychotic drugs
Antipsychotics
Blood
Bone marrow
Case Report
Case reports
Comorbidity
Complications and side effects
Drug dosages
Drug therapy
Hepatitis
Hypertension
Leukopenia
Liver cirrhosis
Neutropenia
Neutrophils
Pathophysiology
Patients
Psychotropic drugs
Schizophrenia
Tumor necrosis factor-TNF
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Summary:Neutropenia is an adverse effect of various pharmacological therapies, including antipsychotics. Among the second-generation antipsychotic (SGA) medications, clozapine is most notable for neutropenic adverse effect. Risperidone, another SGA drug, is linked mainly with metabolic adverse effects, but rarely, blood dyscrasia adverse reactions have been reported. Hence, we report the case of a 56-year-old African American woman who developed severe neutropenia following two weeks of oral risperidone treatment. Her neutrophil levels returned to normal limits following discontinuation of risperidone and switching to haloperidol.
ISSN:2090-682X
2090-6838
DOI:10.1155/2021/3980872