CHEMICAL CONSTITUENTS FROM THE STEM BARK OF Annona pickelii (Annonaceae)

The phytochemical investigation of the stem bark of Annona pickelii yielded four steroids (β-sitostenone, β-sitosterol, stigmasterol and campesterol), three lignans (eudesmin, magnolin and yangambin), twelve alkaloids (liriodenine, lysicamine, atherospermidine, anonaine, analobine, asimilobine, disc...

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Bibliographic Details
Published in:Química Nova 2015-07, Vol.38 (6), p.769-776
Main Authors: Costa, Emmanoel Vilaça, Sampaio, Marília Fernanda Chaves, Salvador, Marcos José, Nepel, Angelita, Barison, Andersson
Format: Article
Language:English
Subjects:
alkaloids
Annona pickelii
Annonaceae
CHEMISTRY, MULTIDISCIPLINARY
lignans
NMR
steroids
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Summary:The phytochemical investigation of the stem bark of Annona pickelii yielded four steroids (β-sitostenone, β-sitosterol, stigmasterol and campesterol), three lignans (eudesmin, magnolin and yangambin), twelve alkaloids (liriodenine, lysicamine, atherospermidine, anonaine, analobine, asimilobine, discretamine, stepholidine, coclaurine, orientaline, juziphine and stepharine), and a benzenoid (2-methoxybenzoic acid). These compounds support their recent reclassification from Rollinia to Annona , and that it is a typical species of the family Annonaceae. Significant antifungal and antioxidant activities were found for the methanol crude extract as well as for the lignans eudesmin, magnolin, yangambin and the alkaloid discretamine. In addition, several items of NMR data for the alkaloids were reviewed and unequivocally described in this work.
ISSN:0100-4042
1678-7064
DOI:10.5935/0100-4042.20150069