Metabolic syndrome and its components predict the development of arterial stiffening in a sample of adult men

Metabolic syndrome (MS) and its components are associated with greater cardiovascular risk. A number of studies found a positive association between MS and vascular damage, but few observational studies evaluated the predictive role of MS on arterial stiffening (AS). Therefore, the aim of this study...

Full description

Saved in:
Bibliographic Details
Published in:Clinical and experimental hypertension (1993) 2022-01, Vol.44 (1), p.26-33
Main Authors: D'Elia, Lanfranco, Barbato, Antonio, Iacone, Roberto, Russo, Ornella, Strazzullo, Pasquale, Galletti, Ferruccio
Format: Article
Language:English
Subjects:
Adult
Arterial stiffening
Arteries
Blood Pressure
Humans
Male
metabolic syndrome
Metabolic Syndrome - epidemiology
Prospective Studies
pulse pressure
Risk Factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Metabolic syndrome (MS) and its components are associated with greater cardiovascular risk. A number of studies found a positive association between MS and vascular damage, but few observational studies evaluated the predictive role of MS on arterial stiffening (AS). Therefore, the aim of this study was to estimate the ability of MS and its components to predict the risk of AS in an 8-year follow-up of a sample of adult men (Olivetti Heart Study). The analysis included 778 men without AS (pulse pressure >60 mmHg) at baseline. A positive diagnosis of MS was made by recognized criteria, if at least three components were present. At the end of the follow-up period, there was an incidence of 11% in AS. The percentage of participants that developed AS was greater in the MS group than those without MS, also after adjustment for main confounders (odds ratio: 2.5, 95% confidence interval: 1.3-4.9). The risk of AS also increased with increase in the numbers of MS elements (p for trend
ISSN:1064-1963
1525-6006
DOI:10.1080/10641963.2021.1969664