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Childhood nosocomial viral acute respiratory tract infections in teaching hospital Anuradhapura, Sri Lanka
We have assessed the risk factors for the occurrence of hospital-acquired (HA) and community-acquired (CA) viral acute respiratory tract infections (ARTIs) in children. Children (1-60 months) who were having ARTI on admission (CA) and develops ARTI following 48 h after admission or 3 days of dischar...
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Published in: | BMC research notes 2019-09, Vol.12 (1), p.581-581 |
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description | We have assessed the risk factors for the occurrence of hospital-acquired (HA) and community-acquired (CA) viral acute respiratory tract infections (ARTIs) in children. Children (1-60 months) who were having ARTI on admission (CA) and develops ARTI following 48 h after admission or 3 days of discharge (HA) were included. Indirect immunofluorescence assay (IFA) was performed and multivariable analyses were done to determine the risk factors for the development of viral CA and HA-ARTI.
Total of 818 with ARTIs, 226 (27.6%) RSV cases were detected. Out of 226, 86 (38.0%) HA-RSV cases were detected. CA-viral-ARTI was significantly high (p |
doi_str_mv | 10.1186/s13104-019-4624-2 |
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Total of 818 with ARTIs, 226 (27.6%) RSV cases were detected. Out of 226, 86 (38.0%) HA-RSV cases were detected. CA-viral-ARTI was significantly high (p < 0.05). Compared to CA-RSV-ARTI immunodeficiency, seizures, trisomy-21 and congenital heart disease (CHD) were having 2.3, 3.2, 1.8- and 2.2-times risk for acquiring HA-RSV respectively. The number of deaths was significantly high following HA-RSV. The associated burden was significant following HA-RSV and it was 429.77 disability-adjusted life years. Children who are having immunodeficiency, CHD, seizure episodes and trisomy 21 would lead to the acquisition of nosocomial RSV infections in great. Adherence to meticulous infection control practices will be helpful to minimize the HA-viral ARTIs in great.</description><identifier>ISSN: 1756-0500</identifier><identifier>EISSN: 1756-0500</identifier><identifier>DOI: 10.1186/s13104-019-4624-2</identifier><identifier>PMID: 31521197</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Acute Disease ; Air pollution ; Child, Preschool ; Childhood ; Children ; Children & youth ; Common Variable Immunodeficiency - complications ; Congenital diseases ; Congenital heart defects ; Coronary artery disease ; Cross infection ; Cross Infection - epidemiology ; Cross Infection - virology ; Cross-Sectional Studies ; Demographic aspects ; Diagnosis ; Down Syndrome - complications ; Female ; Fluorescent antibody technique ; Genetic disorders ; Heart Defects, Congenital - complications ; Heart diseases ; Hospitalization ; Hospitals ; Humans ; Immunodeficiency ; Immunofluorescence ; Infant ; Male ; Malnutrition ; Medical research ; Medicine ; Nosocomial infections ; Nosocomial: viral acute respiratory tract infections ; Patients ; Pediatric respiratory diseases ; Pneumonia ; Research Note ; Respiratory syncytial virus ; Respiratory syncytial virus and risk factors ; Respiratory Syncytial Virus Infections - epidemiology ; Respiratory Syncytial Virus Infections - mortality ; Respiratory Syncytial Virus, Human ; Respiratory tract diseases ; Respiratory tract infection ; Respiratory Tract Infections - epidemiology ; Respiratory Tract Infections - mortality ; Respiratory Tract Infections - virology ; Risk Factors ; Seizures ; Seizures - complications ; Sri Lanka ; Staphylococcus infections ; Teachers ; Teaching hospitals ; Trisomy ; Urogenital system ; Viral infections ; Viruses</subject><ispartof>BMC research notes, 2019-09, Vol.12 (1), p.581-581</ispartof><rights>COPYRIGHT 2019 BioMed Central Ltd.</rights><rights>2019. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><orcidid>0000-0001-5051-530X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744681/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2293268576?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,25731,27901,27902,36989,36990,44566,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31521197$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sampath Jayaweera, Jayaweera Arachchige Asela</creatorcontrib><creatorcontrib>Reyes, Mohammed</creatorcontrib><title>Childhood nosocomial viral acute respiratory tract infections in teaching hospital Anuradhapura, Sri Lanka</title><title>BMC research notes</title><addtitle>BMC Res Notes</addtitle><description>We have assessed the risk factors for the occurrence of hospital-acquired (HA) and community-acquired (CA) viral acute respiratory tract infections (ARTIs) in children. Children (1-60 months) who were having ARTI on admission (CA) and develops ARTI following 48 h after admission or 3 days of discharge (HA) were included. Indirect immunofluorescence assay (IFA) was performed and multivariable analyses were done to determine the risk factors for the development of viral CA and HA-ARTI.
Total of 818 with ARTIs, 226 (27.6%) RSV cases were detected. Out of 226, 86 (38.0%) HA-RSV cases were detected. CA-viral-ARTI was significantly high (p < 0.05). Compared to CA-RSV-ARTI immunodeficiency, seizures, trisomy-21 and congenital heart disease (CHD) were having 2.3, 3.2, 1.8- and 2.2-times risk for acquiring HA-RSV respectively. The number of deaths was significantly high following HA-RSV. The associated burden was significant following HA-RSV and it was 429.77 disability-adjusted life years. Children who are having immunodeficiency, CHD, seizure episodes and trisomy 21 would lead to the acquisition of nosocomial RSV infections in great. Adherence to meticulous infection control practices will be helpful to minimize the HA-viral ARTIs in great.</description><subject>Acute Disease</subject><subject>Air pollution</subject><subject>Child, Preschool</subject><subject>Childhood</subject><subject>Children</subject><subject>Children & youth</subject><subject>Common Variable Immunodeficiency - complications</subject><subject>Congenital diseases</subject><subject>Congenital heart defects</subject><subject>Coronary artery disease</subject><subject>Cross infection</subject><subject>Cross Infection - epidemiology</subject><subject>Cross Infection - virology</subject><subject>Cross-Sectional Studies</subject><subject>Demographic aspects</subject><subject>Diagnosis</subject><subject>Down Syndrome - complications</subject><subject>Female</subject><subject>Fluorescent antibody technique</subject><subject>Genetic disorders</subject><subject>Heart Defects, Congenital - complications</subject><subject>Heart diseases</subject><subject>Hospitalization</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Immunodeficiency</subject><subject>Immunofluorescence</subject><subject>Infant</subject><subject>Male</subject><subject>Malnutrition</subject><subject>Medical research</subject><subject>Medicine</subject><subject>Nosocomial infections</subject><subject>Nosocomial: viral acute respiratory tract infections</subject><subject>Patients</subject><subject>Pediatric respiratory diseases</subject><subject>Pneumonia</subject><subject>Research Note</subject><subject>Respiratory syncytial virus</subject><subject>Respiratory syncytial virus and risk factors</subject><subject>Respiratory Syncytial Virus Infections - epidemiology</subject><subject>Respiratory Syncytial Virus Infections - mortality</subject><subject>Respiratory Syncytial Virus, Human</subject><subject>Respiratory tract diseases</subject><subject>Respiratory tract infection</subject><subject>Respiratory Tract Infections - epidemiology</subject><subject>Respiratory Tract Infections - mortality</subject><subject>Respiratory Tract Infections - virology</subject><subject>Risk Factors</subject><subject>Seizures</subject><subject>Seizures - complications</subject><subject>Sri Lanka</subject><subject>Staphylococcus infections</subject><subject>Teachers</subject><subject>Teaching hospitals</subject><subject>Trisomy</subject><subject>Urogenital system</subject><subject>Viral infections</subject><subject>Viruses</subject><issn>1756-0500</issn><issn>1756-0500</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNptkluL1DAUx4so7kU_gC9S8MUFuyZNmqQvC8PgZWBgH7y8htMkbTN2kjFJF_fbm3FX3YoEci75nT_knFMULzC6xFiwtxETjGiFcFtRVtOqflScYt6wCjUIPX7gnxRnMe4QYlgI_LQ4IbipMW75abFbj3bSo_e6dD565fcWpvLGhnyDmpMpg4mHHCYfbssUQKXSut6oZL2L2S2TATVaN5Sjz2DKdSs3B9AjHLJ5U34KttyC-wbPiic9TNE8v7fnxZf37z6vP1bb6w-b9WpbacpwqhjXums5Mpw0gilCa9Zo3DW0Q4KqGhrRCd0YYILUoIGDoY0AQIoIpIzoyXmxudPVHnbyEOwewq30YOWvhA-DhJCsmozsWw5MdR3HfU1N1lMccA6JJgaM0Fnr6k7rMHd7o5VxuQXTQnT54uwoB38jGaeUCZwFXt8LBP99NjHJvY3KTBM44-co67pFLSeMkYy--gfd-Tm43KojRWomGs7-UgPkD-RR-ONQjqJyxVBeBcEZzdTlf6h8tNlb5Z3pbc4vCi4WBZlJ5kcaYI5Rbq6_LtmXD5vypxu_t4r8BFHCzwQ</recordid><startdate>20190914</startdate><enddate>20190914</enddate><creator>Sampath Jayaweera, Jayaweera Arachchige Asela</creator><creator>Reyes, Mohammed</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><general>BMC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>IOV</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0001-5051-530X</orcidid></search><sort><creationdate>20190914</creationdate><title>Childhood nosocomial viral acute respiratory tract infections in teaching hospital Anuradhapura, Sri Lanka</title><author>Sampath Jayaweera, Jayaweera Arachchige Asela ; Reyes, Mohammed</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-d461t-67ddb970e73586c34265d1b54b084c2a58b8d5ea6832ada7ae458aa0c380ce8f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Acute Disease</topic><topic>Air pollution</topic><topic>Child, Preschool</topic><topic>Childhood</topic><topic>Children</topic><topic>Children & youth</topic><topic>Common Variable Immunodeficiency - complications</topic><topic>Congenital diseases</topic><topic>Congenital heart defects</topic><topic>Coronary artery disease</topic><topic>Cross infection</topic><topic>Cross Infection - epidemiology</topic><topic>Cross Infection - virology</topic><topic>Cross-Sectional Studies</topic><topic>Demographic aspects</topic><topic>Diagnosis</topic><topic>Down Syndrome - complications</topic><topic>Female</topic><topic>Fluorescent antibody technique</topic><topic>Genetic disorders</topic><topic>Heart Defects, Congenital - complications</topic><topic>Heart diseases</topic><topic>Hospitalization</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Immunodeficiency</topic><topic>Immunofluorescence</topic><topic>Infant</topic><topic>Male</topic><topic>Malnutrition</topic><topic>Medical research</topic><topic>Medicine</topic><topic>Nosocomial infections</topic><topic>Nosocomial: viral acute respiratory tract infections</topic><topic>Patients</topic><topic>Pediatric respiratory diseases</topic><topic>Pneumonia</topic><topic>Research Note</topic><topic>Respiratory syncytial virus</topic><topic>Respiratory syncytial virus and risk factors</topic><topic>Respiratory Syncytial Virus Infections - epidemiology</topic><topic>Respiratory Syncytial Virus Infections - mortality</topic><topic>Respiratory Syncytial Virus, Human</topic><topic>Respiratory tract diseases</topic><topic>Respiratory tract infection</topic><topic>Respiratory Tract Infections - epidemiology</topic><topic>Respiratory Tract Infections - mortality</topic><topic>Respiratory Tract Infections - virology</topic><topic>Risk Factors</topic><topic>Seizures</topic><topic>Seizures - complications</topic><topic>Sri Lanka</topic><topic>Staphylococcus infections</topic><topic>Teachers</topic><topic>Teaching hospitals</topic><topic>Trisomy</topic><topic>Urogenital system</topic><topic>Viral infections</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sampath Jayaweera, Jayaweera Arachchige Asela</creatorcontrib><creatorcontrib>Reyes, Mohammed</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Opposing Viewpoints In Context</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection (Proquest)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biological Sciences</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Biological Science Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>BMC research notes</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sampath Jayaweera, Jayaweera Arachchige Asela</au><au>Reyes, Mohammed</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Childhood nosocomial viral acute respiratory tract infections in teaching hospital Anuradhapura, Sri Lanka</atitle><jtitle>BMC research notes</jtitle><addtitle>BMC Res Notes</addtitle><date>2019-09-14</date><risdate>2019</risdate><volume>12</volume><issue>1</issue><spage>581</spage><epage>581</epage><pages>581-581</pages><issn>1756-0500</issn><eissn>1756-0500</eissn><abstract>We have assessed the risk factors for the occurrence of hospital-acquired (HA) and community-acquired (CA) viral acute respiratory tract infections (ARTIs) in children. Children (1-60 months) who were having ARTI on admission (CA) and develops ARTI following 48 h after admission or 3 days of discharge (HA) were included. Indirect immunofluorescence assay (IFA) was performed and multivariable analyses were done to determine the risk factors for the development of viral CA and HA-ARTI.
Total of 818 with ARTIs, 226 (27.6%) RSV cases were detected. Out of 226, 86 (38.0%) HA-RSV cases were detected. CA-viral-ARTI was significantly high (p < 0.05). Compared to CA-RSV-ARTI immunodeficiency, seizures, trisomy-21 and congenital heart disease (CHD) were having 2.3, 3.2, 1.8- and 2.2-times risk for acquiring HA-RSV respectively. The number of deaths was significantly high following HA-RSV. The associated burden was significant following HA-RSV and it was 429.77 disability-adjusted life years. Children who are having immunodeficiency, CHD, seizure episodes and trisomy 21 would lead to the acquisition of nosocomial RSV infections in great. Adherence to meticulous infection control practices will be helpful to minimize the HA-viral ARTIs in great.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>31521197</pmid><doi>10.1186/s13104-019-4624-2</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0001-5051-530X</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Acute Disease Air pollution Child, Preschool Childhood Children Children & youth Common Variable Immunodeficiency - complications Congenital diseases Congenital heart defects Coronary artery disease Cross infection Cross Infection - epidemiology Cross Infection - virology Cross-Sectional Studies Demographic aspects Diagnosis Down Syndrome - complications Female Fluorescent antibody technique Genetic disorders Heart Defects, Congenital - complications Heart diseases Hospitalization Hospitals Humans Immunodeficiency Immunofluorescence Infant Male Malnutrition Medical research Medicine Nosocomial infections Nosocomial: viral acute respiratory tract infections Patients Pediatric respiratory diseases Pneumonia Research Note Respiratory syncytial virus Respiratory syncytial virus and risk factors Respiratory Syncytial Virus Infections - epidemiology Respiratory Syncytial Virus Infections - mortality Respiratory Syncytial Virus, Human Respiratory tract diseases Respiratory tract infection Respiratory Tract Infections - epidemiology Respiratory Tract Infections - mortality Respiratory Tract Infections - virology Risk Factors Seizures Seizures - complications Sri Lanka Staphylococcus infections Teachers Teaching hospitals Trisomy Urogenital system Viral infections Viruses |
title | Childhood nosocomial viral acute respiratory tract infections in teaching hospital Anuradhapura, Sri Lanka |
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