Clinical outcomes of pediatric osteomyelitis

Osteomyelitis in children may produce severe sequelae. However, the frequency and distribution of such complications by type of osteomyelitis (chronic or acute) is not well described. We searched the HealthFacts® database (containing medical information on 68 million individual patients in the Unite...

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Bibliographic Details
Published in:BMC pediatrics 2023-02, Vol.23 (1), p.54-54, Article 54
Main Authors: Disch, Kylie, Hill, Deirdre A, Snow, Harry, Dehority, Walter
Format: Article
Language:English
Subjects:
Acute Disease
Arthritis
Child
Children
Clinical outcomes
Datasets
Demographic aspects
Diagnosis
Disease Progression
Diseases
Female
Fracture
Fractures
Fractures, Spontaneous - surgery
Humans
Male
Microbiology
Organisms
Orthopedics
Osteomyelitis
Osteomyelitis - complications
Osteomyelitis - diagnosis
Osteomyelitis - therapy
Pathogens
Pathologic fracture
Patient outcomes
Pediatrics
Retrospective Studies
Staphylococcus infections
Statistical significance
Surgery
United States
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Summary:Osteomyelitis in children may produce severe sequelae. However, the frequency and distribution of such complications by type of osteomyelitis (chronic or acute) is not well described. We searched the HealthFacts® database (containing medical information on 68 million individual patients in the United States) with 238 International Classification of Diseases (ICD) version 10 codes for acute osteomyelitis and chronic osteomyelitis appearing in 2015. Outcomes were recorded for each subject, including development of limb length discrepancies, pathologic fractures, mortality, and need for multiple surgeries or prolonged orthopedic care (one to two years following diagnosis). Gender, age and season of diagnosis were also assessed. Chi-square tests were used to compare differences between categorical variables, and t-tests between continuous variables. Eight hundred sixty-nine subjects were included (57.4% male). Children with chronic osteomyelitis were older than those with acute osteomyelitis (median 9.5 years vs 12.0, respectively, p = .0004). Diagnoses were more common in winter (p = .0003). Four subjects died while hospitalized during the study period (two with acute osteomyelitis, two with chronic osteomyelitis). Limb length discrepancies were rare and similarly distributed between infection types (≤ 1.3% of subjects, p = .83). Subjects with chronic osteomyeltis were more likely to require long-term orthopedic follow-up (14.0% vs. 4.8% for acute osteomyelitis, p 
ISSN:1471-2431
1471-2431
DOI:10.1186/s12887-023-03863-z