Melatonin as a powerful antioxidant

Melatonin is a hormone that has many body functions and, for several decades, its antioxidant potential has been increasingly talked about. There is a relationship between failure in melatonin production in the pineal gland, an insufficient supply of this hormone to the body, and the occurrence of f...

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Bibliographic Details
Published in:Acta pharmaceutica (Zagreb, Croatia) Croatia), 2021-09, Vol.71 (3), p.335-354
Main Authors: Chrustek, Agnieszka, Olszewska-Słonina, Dorota
Format: Article
Language:English
Subjects:
Aging
Antioxidants
Cardiovascular diseases
Diabetes mellitus
Etiology
Free radicals
In vivo methods and tests
Insomnia
lipid peroxidation
Melatonin
Molecular biology
Neurodegenerative diseases
Oxidative stress
Pineal gland
Sleep disorders
Supplements
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Summary:Melatonin is a hormone that has many body functions and, for several decades, its antioxidant potential has been increasingly talked about. There is a relationship between failure in melatonin production in the pineal gland, an insufficient supply of this hormone to the body, and the occurrence of free radical etiology diseases such as neurodegenerative diseases, cardiovascular diseases, diabetes, cancer and others. Despite the development of molecular biology, numerous and studies, the exact mechanism of melatonin antioxidant activity is still unknown. Nowadays, the use of melatonin supplementation is more and more common, not only to prevent insomnia, but also to slow down the aging process and provide protection against diseases. The aim of this study is to get acquainted with current reports on melatonin, antioxidative mechanisms and their importance in diseases of free radical etiology.
ISSN:1846-9558
1330-0075
1846-9558
DOI:10.2478/acph-2021-0027