Reference group choice and antibiotic resistance outcomes

Two types of cohort studies examining patients infected with methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) were contrasted, using different reference groups. Cases were compared to uninfected patients and patients infected with the corresponding, susce...

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Bibliographic Details
Published in:Emerging infectious diseases 2004-06, Vol.10 (6), p.1125-1128
Main Authors: Kaye, Keith S, Engemann, John J, Mozaffari, Essy, Carmeli, Yehuda
Format: Article
Language:English
Subjects:
Antibiotics
antimicrobial resistance
Cohort Studies
Control Groups
cost
Dispatch
Enterococcus
Hospitalization - economics
Humans
Methicillin Resistance
methodology
Multivariate Analysis
outcomes
Staphylococcal Infections - drug therapy
Staphylococcal Infections - economics
Staphylococcus aureus
Vancomycin Resistance
Wound Infection - drug therapy
Wound Infection - economics
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Summary:Two types of cohort studies examining patients infected with methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) were contrasted, using different reference groups. Cases were compared to uninfected patients and patients infected with the corresponding, susceptible organism. VRE and MRSA were associated with adverse outcomes. The effect was greater when uninfected control patients were used.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid1006.020665