Acute Polyserositis with Cardiac Tamponade and Bilateral Refractory Pleural Effusion after ChAdOx1 nCoV-19 Vaccination

The association of SARS-CoV-2 messenger ribonucleic acid vaccines with pericarditis in young adults has been reported. However, data regarding other types of vaccines are extremely limited. We presented a 94-year-old man with rapidly progressive dyspnea and fatigue six days after his first ChAdOx1 n...

Full description

Saved in:
Bibliographic Details
Published in:Vaccines (Basel) 2022-08, Vol.10 (8), p.1286
Main Authors: Li, Guan-Yi, Lee, Chang-Ching, Huang, Chin-Chou
Format: Article
Language:English
Subjects:
Autoimmune diseases
Biopsy
Blood pressure
cardiac tamponade
Cardiovascular disease
Case Report
Catheters
ChAdOx1 nCoV-19
Colchicine
Coronaviruses
COVID-19
COVID-19 vaccines
Diagnosis
Dyspnea
Granulomas
Heart
Heart failure
Hospitalization
Infections
Inflammation
Lupus
Myocarditis
Pandemics
Peptides
Pericarditis
Pleural effusion
Pleural effusions
Pleurisy
Polymerase chain reaction
Polyserositis
Prednisolone
Respiration
Ribonucleic acid
Risk factors
RNA
Severe acute respiratory syndrome coronavirus 2
Tamponade
Thyroid gland
Tuberculosis
vaccine
Vaccines
Vectors (Biology)
Young adults
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c501t-8693f01706f8b6dc12b710d2d0714ff2c7c95dafb431b994f8d677ee32b47dc13
cites cdi_FETCH-LOGICAL-c501t-8693f01706f8b6dc12b710d2d0714ff2c7c95dafb431b994f8d677ee32b47dc13
container_end_page
container_issue 8
container_start_page 1286
container_title Vaccines (Basel)
container_volume 10
creator Li, Guan-Yi
Lee, Chang-Ching
Huang, Chin-Chou
description The association of SARS-CoV-2 messenger ribonucleic acid vaccines with pericarditis in young adults has been reported. However, data regarding other types of vaccines are extremely limited. We presented a 94-year-old man with rapidly progressive dyspnea and fatigue six days after his first ChAdOx1 nCoV-19 vaccination. Impending cardiac tamponade and bilateral pleural effusion were found. Hence, massive yellowish pericardial and pleural effusion were drained. However, the pleural effusion persisted and pigtail catheters were inserted bilaterally. After serial studies including surgical pleural biopsy, acute polyserositis (pericarditis and pleurisy) was diagnosed. Anti-inflammatory treatment with colchicine and prednisolone was administered. All effusions resolved accordingly. This rare case sheds light on the presentation of ChAdOx1 nCoV-19 vaccine-related acute polyserositis. In conclusion, awareness of this potential adverse event may facilitate the diagnosis for unexplained pericardial or pleural effusion after vaccination.
doi_str_mv 10.3390/vaccines10081286
format article
fullrecord <record><control><sourceid>gale_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_fabd591cbad1428787d37f870366d26d</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A746716662</galeid><doaj_id>oai_doaj_org_article_fabd591cbad1428787d37f870366d26d</doaj_id><sourcerecordid>A746716662</sourcerecordid><originalsourceid>FETCH-LOGICAL-c501t-8693f01706f8b6dc12b710d2d0714ff2c7c95dafb431b994f8d677ee32b47dc13</originalsourceid><addsrcrecordid>eNptkk1r3DAQhk1paUKae4-Cnp3qw5asS2FrkiYQSChp6E3I-tjVYktbSd52_3202dB2S6WDhtE7D-8wU1XvEbwghMOPW6mU8yYhCDuEO_qqOsWQ0Zpw8v31X_FJdZ7SGpbDEekoe1udEAoRRaw5rbYLNWcD7sO4SyaG5LJL4KfLK9DLqJ1U4EFOm-ClNkB6DT67UWYT5Qi-GhulyiHuwP1o5n3q0to5ueCBtEUD-tVC3_1CwPfhsUYcPD4blrko3lVvrByTOX95z6pvV5cP_XV9e_flpl_c1qqFKNcd5cRCxCC13UC1QnhgCGqsIUONtVgxxVst7dAQNHDe2E5TxowheGhYkZOz6ubA1UGuxSa6ScadCNKJ50SISyFjdmo0wspBtxypQWrU4I51TBNmOwYJpRpTXVifDqzNPExGK-NzafoIevzj3Uosw1bwBrUtggXw4QUQw4_ZpCzWYY6-9C9wabGMEEL8R7WUxZXzNhSYmlxSYsEayhCldK-6-I-qXG0mp4I31pX8UQE8FKgy5RSN_W0cQbHfJ_HvPpEnTIi9tw</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2706286002</pqid></control><display><type>article</type><title>Acute Polyserositis with Cardiac Tamponade and Bilateral Refractory Pleural Effusion after ChAdOx1 nCoV-19 Vaccination</title><source>Publicly Available Content Database (Proquest) (PQ_SDU_P3)</source><source>PubMed Central</source><creator>Li, Guan-Yi ; Lee, Chang-Ching ; Huang, Chin-Chou</creator><creatorcontrib>Li, Guan-Yi ; Lee, Chang-Ching ; Huang, Chin-Chou</creatorcontrib><description>The association of SARS-CoV-2 messenger ribonucleic acid vaccines with pericarditis in young adults has been reported. However, data regarding other types of vaccines are extremely limited. We presented a 94-year-old man with rapidly progressive dyspnea and fatigue six days after his first ChAdOx1 nCoV-19 vaccination. Impending cardiac tamponade and bilateral pleural effusion were found. Hence, massive yellowish pericardial and pleural effusion were drained. However, the pleural effusion persisted and pigtail catheters were inserted bilaterally. After serial studies including surgical pleural biopsy, acute polyserositis (pericarditis and pleurisy) was diagnosed. Anti-inflammatory treatment with colchicine and prednisolone was administered. All effusions resolved accordingly. This rare case sheds light on the presentation of ChAdOx1 nCoV-19 vaccine-related acute polyserositis. In conclusion, awareness of this potential adverse event may facilitate the diagnosis for unexplained pericardial or pleural effusion after vaccination.</description><identifier>ISSN: 2076-393X</identifier><identifier>EISSN: 2076-393X</identifier><identifier>DOI: 10.3390/vaccines10081286</identifier><identifier>PMID: 36016174</identifier><language>eng</language><publisher>Basel: MDPI AG</publisher><subject>Autoimmune diseases ; Biopsy ; Blood pressure ; cardiac tamponade ; Cardiovascular disease ; Case Report ; Catheters ; ChAdOx1 nCoV-19 ; Colchicine ; Coronaviruses ; COVID-19 ; COVID-19 vaccines ; Diagnosis ; Dyspnea ; Granulomas ; Heart ; Heart failure ; Hospitalization ; Infections ; Inflammation ; Lupus ; Myocarditis ; Pandemics ; Peptides ; Pericarditis ; Pleural effusion ; Pleural effusions ; Pleurisy ; Polymerase chain reaction ; Polyserositis ; Prednisolone ; Respiration ; Ribonucleic acid ; Risk factors ; RNA ; Severe acute respiratory syndrome coronavirus 2 ; Tamponade ; Thyroid gland ; Tuberculosis ; vaccine ; Vaccines ; Vectors (Biology) ; Young adults</subject><ispartof>Vaccines (Basel), 2022-08, Vol.10 (8), p.1286</ispartof><rights>COPYRIGHT 2022 MDPI AG</rights><rights>2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2022 by the authors. 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c501t-8693f01706f8b6dc12b710d2d0714ff2c7c95dafb431b994f8d677ee32b47dc13</citedby><cites>FETCH-LOGICAL-c501t-8693f01706f8b6dc12b710d2d0714ff2c7c95dafb431b994f8d677ee32b47dc13</cites><orcidid>0000-0002-4217-8734</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2706286002/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2706286002?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,44590,53791,53793,74998</link.rule.ids></links><search><creatorcontrib>Li, Guan-Yi</creatorcontrib><creatorcontrib>Lee, Chang-Ching</creatorcontrib><creatorcontrib>Huang, Chin-Chou</creatorcontrib><title>Acute Polyserositis with Cardiac Tamponade and Bilateral Refractory Pleural Effusion after ChAdOx1 nCoV-19 Vaccination</title><title>Vaccines (Basel)</title><description>The association of SARS-CoV-2 messenger ribonucleic acid vaccines with pericarditis in young adults has been reported. However, data regarding other types of vaccines are extremely limited. We presented a 94-year-old man with rapidly progressive dyspnea and fatigue six days after his first ChAdOx1 nCoV-19 vaccination. Impending cardiac tamponade and bilateral pleural effusion were found. Hence, massive yellowish pericardial and pleural effusion were drained. However, the pleural effusion persisted and pigtail catheters were inserted bilaterally. After serial studies including surgical pleural biopsy, acute polyserositis (pericarditis and pleurisy) was diagnosed. Anti-inflammatory treatment with colchicine and prednisolone was administered. All effusions resolved accordingly. This rare case sheds light on the presentation of ChAdOx1 nCoV-19 vaccine-related acute polyserositis. In conclusion, awareness of this potential adverse event may facilitate the diagnosis for unexplained pericardial or pleural effusion after vaccination.</description><subject>Autoimmune diseases</subject><subject>Biopsy</subject><subject>Blood pressure</subject><subject>cardiac tamponade</subject><subject>Cardiovascular disease</subject><subject>Case Report</subject><subject>Catheters</subject><subject>ChAdOx1 nCoV-19</subject><subject>Colchicine</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>COVID-19 vaccines</subject><subject>Diagnosis</subject><subject>Dyspnea</subject><subject>Granulomas</subject><subject>Heart</subject><subject>Heart failure</subject><subject>Hospitalization</subject><subject>Infections</subject><subject>Inflammation</subject><subject>Lupus</subject><subject>Myocarditis</subject><subject>Pandemics</subject><subject>Peptides</subject><subject>Pericarditis</subject><subject>Pleural effusion</subject><subject>Pleural effusions</subject><subject>Pleurisy</subject><subject>Polymerase chain reaction</subject><subject>Polyserositis</subject><subject>Prednisolone</subject><subject>Respiration</subject><subject>Ribonucleic acid</subject><subject>Risk factors</subject><subject>RNA</subject><subject>Severe acute respiratory syndrome coronavirus 2</subject><subject>Tamponade</subject><subject>Thyroid gland</subject><subject>Tuberculosis</subject><subject>vaccine</subject><subject>Vaccines</subject><subject>Vectors (Biology)</subject><subject>Young adults</subject><issn>2076-393X</issn><issn>2076-393X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNptkk1r3DAQhk1paUKae4-Cnp3qw5asS2FrkiYQSChp6E3I-tjVYktbSd52_3202dB2S6WDhtE7D-8wU1XvEbwghMOPW6mU8yYhCDuEO_qqOsWQ0Zpw8v31X_FJdZ7SGpbDEekoe1udEAoRRaw5rbYLNWcD7sO4SyaG5LJL4KfLK9DLqJ1U4EFOm-ClNkB6DT67UWYT5Qi-GhulyiHuwP1o5n3q0to5ueCBtEUD-tVC3_1CwPfhsUYcPD4blrko3lVvrByTOX95z6pvV5cP_XV9e_flpl_c1qqFKNcd5cRCxCC13UC1QnhgCGqsIUONtVgxxVst7dAQNHDe2E5TxowheGhYkZOz6ubA1UGuxSa6ScadCNKJ50SISyFjdmo0wspBtxypQWrU4I51TBNmOwYJpRpTXVifDqzNPExGK-NzafoIevzj3Uosw1bwBrUtggXw4QUQw4_ZpCzWYY6-9C9wabGMEEL8R7WUxZXzNhSYmlxSYsEayhCldK-6-I-qXG0mp4I31pX8UQE8FKgy5RSN_W0cQbHfJ_HvPpEnTIi9tw</recordid><startdate>20220801</startdate><enddate>20220801</enddate><creator>Li, Guan-Yi</creator><creator>Lee, Chang-Ching</creator><creator>Huang, Chin-Chou</creator><general>MDPI AG</general><general>MDPI</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T7</scope><scope>7XB</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>P64</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-4217-8734</orcidid></search><sort><creationdate>20220801</creationdate><title>Acute Polyserositis with Cardiac Tamponade and Bilateral Refractory Pleural Effusion after ChAdOx1 nCoV-19 Vaccination</title><author>Li, Guan-Yi ; Lee, Chang-Ching ; Huang, Chin-Chou</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c501t-8693f01706f8b6dc12b710d2d0714ff2c7c95dafb431b994f8d677ee32b47dc13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Autoimmune diseases</topic><topic>Biopsy</topic><topic>Blood pressure</topic><topic>cardiac tamponade</topic><topic>Cardiovascular disease</topic><topic>Case Report</topic><topic>Catheters</topic><topic>ChAdOx1 nCoV-19</topic><topic>Colchicine</topic><topic>Coronaviruses</topic><topic>COVID-19</topic><topic>COVID-19 vaccines</topic><topic>Diagnosis</topic><topic>Dyspnea</topic><topic>Granulomas</topic><topic>Heart</topic><topic>Heart failure</topic><topic>Hospitalization</topic><topic>Infections</topic><topic>Inflammation</topic><topic>Lupus</topic><topic>Myocarditis</topic><topic>Pandemics</topic><topic>Peptides</topic><topic>Pericarditis</topic><topic>Pleural effusion</topic><topic>Pleural effusions</topic><topic>Pleurisy</topic><topic>Polymerase chain reaction</topic><topic>Polyserositis</topic><topic>Prednisolone</topic><topic>Respiration</topic><topic>Ribonucleic acid</topic><topic>Risk factors</topic><topic>RNA</topic><topic>Severe acute respiratory syndrome coronavirus 2</topic><topic>Tamponade</topic><topic>Thyroid gland</topic><topic>Tuberculosis</topic><topic>vaccine</topic><topic>Vaccines</topic><topic>Vectors (Biology)</topic><topic>Young adults</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Li, Guan-Yi</creatorcontrib><creatorcontrib>Lee, Chang-Ching</creatorcontrib><creatorcontrib>Huang, Chin-Chou</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>Biological Sciences</collection><collection>ProQuest_Research Library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Publicly Available Content Database (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Open Access: DOAJ - Directory of Open Access Journals</collection><jtitle>Vaccines (Basel)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Guan-Yi</au><au>Lee, Chang-Ching</au><au>Huang, Chin-Chou</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Acute Polyserositis with Cardiac Tamponade and Bilateral Refractory Pleural Effusion after ChAdOx1 nCoV-19 Vaccination</atitle><jtitle>Vaccines (Basel)</jtitle><date>2022-08-01</date><risdate>2022</risdate><volume>10</volume><issue>8</issue><spage>1286</spage><pages>1286-</pages><issn>2076-393X</issn><eissn>2076-393X</eissn><abstract>The association of SARS-CoV-2 messenger ribonucleic acid vaccines with pericarditis in young adults has been reported. However, data regarding other types of vaccines are extremely limited. We presented a 94-year-old man with rapidly progressive dyspnea and fatigue six days after his first ChAdOx1 nCoV-19 vaccination. Impending cardiac tamponade and bilateral pleural effusion were found. Hence, massive yellowish pericardial and pleural effusion were drained. However, the pleural effusion persisted and pigtail catheters were inserted bilaterally. After serial studies including surgical pleural biopsy, acute polyserositis (pericarditis and pleurisy) was diagnosed. Anti-inflammatory treatment with colchicine and prednisolone was administered. All effusions resolved accordingly. This rare case sheds light on the presentation of ChAdOx1 nCoV-19 vaccine-related acute polyserositis. In conclusion, awareness of this potential adverse event may facilitate the diagnosis for unexplained pericardial or pleural effusion after vaccination.</abstract><cop>Basel</cop><pub>MDPI AG</pub><pmid>36016174</pmid><doi>10.3390/vaccines10081286</doi><orcidid>https://orcid.org/0000-0002-4217-8734</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2076-393X
ispartof Vaccines (Basel), 2022-08, Vol.10 (8), p.1286
issn 2076-393X
2076-393X
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_fabd591cbad1428787d37f870366d26d
source Publicly Available Content Database (Proquest) (PQ_SDU_P3); PubMed Central
subjects Autoimmune diseases
Biopsy
Blood pressure
cardiac tamponade
Cardiovascular disease
Case Report
Catheters
ChAdOx1 nCoV-19
Colchicine
Coronaviruses
COVID-19
COVID-19 vaccines
Diagnosis
Dyspnea
Granulomas
Heart
Heart failure
Hospitalization
Infections
Inflammation
Lupus
Myocarditis
Pandemics
Peptides
Pericarditis
Pleural effusion
Pleural effusions
Pleurisy
Polymerase chain reaction
Polyserositis
Prednisolone
Respiration
Ribonucleic acid
Risk factors
RNA
Severe acute respiratory syndrome coronavirus 2
Tamponade
Thyroid gland
Tuberculosis
vaccine
Vaccines
Vectors (Biology)
Young adults
title Acute Polyserositis with Cardiac Tamponade and Bilateral Refractory Pleural Effusion after ChAdOx1 nCoV-19 Vaccination
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T14%3A09%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Acute%20Polyserositis%20with%20Cardiac%20Tamponade%20and%20Bilateral%20Refractory%20Pleural%20Effusion%20after%20ChAdOx1%20nCoV-19%20Vaccination&rft.jtitle=Vaccines%20(Basel)&rft.au=Li,%20Guan-Yi&rft.date=2022-08-01&rft.volume=10&rft.issue=8&rft.spage=1286&rft.pages=1286-&rft.issn=2076-393X&rft.eissn=2076-393X&rft_id=info:doi/10.3390/vaccines10081286&rft_dat=%3Cgale_doaj_%3EA746716662%3C/gale_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c501t-8693f01706f8b6dc12b710d2d0714ff2c7c95dafb431b994f8d677ee32b47dc13%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2706286002&rft_id=info:pmid/36016174&rft_galeid=A746716662&rfr_iscdi=true