Unusual antithyroid drug-induced hypoglycemia

Insulin autoimmune syndrome is defined as the occurrence of spontaneous hypoglycemia attacks with high titers of anti-insulin autoantibodies in patients with no previous exposure to insulin. This rare syndrome has mostly been reported from the Japanese population and is frequently associated with ot...

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Bibliographic Details
Published in:Chrismed journal of health and research 2017-07, Vol.4 (3), p.198-200
Main Authors: Manish Gutch, Annesh Bhattacharya, Sukriti Kumar, Rajendra Kumar Pahan, Rao Somendra Singh
Format: Article
Language:English
Subjects:
Anti-insulin antibody
carbimazole
Graves' disease
hypoglycemia
insulin autoimmune syndrome
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Summary:Insulin autoimmune syndrome is defined as the occurrence of spontaneous hypoglycemia attacks with high titers of anti-insulin autoantibodies in patients with no previous exposure to insulin. This rare syndrome has mostly been reported from the Japanese population and is frequently associated with other autoimmune conditions and certain drugs, especially those containing a sulfhydryl group. Most cases undergo spontaneous remission following removal of the offending drug. We hereby describe the case of a female who developed this rare syndrome following intake of carbimazole for Graves' disease.
ISSN:2348-3334
2348-506X
DOI:10.4103/cjhr.cjhr_14_17