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Determinants of health-related quality of life in older people with chronic musculoskeletal pain: a cross-sectional study
This study aimed to identify the significant physical, psychological, and social determinants associated with EuroQuol-5D (EQ-5D) among Chinese older people with chronic musculoskeletal pain, and to evaluate how these determinants affected the five dimensions of EQ-5D. This is a cross-sectional stud...
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Published in: | BMC geriatrics 2024-01, Vol.24 (1), p.119-8, Article 119 |
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description | This study aimed to identify the significant physical, psychological, and social determinants associated with EuroQuol-5D (EQ-5D) among Chinese older people with chronic musculoskeletal pain, and to evaluate how these determinants affected the five dimensions of EQ-5D.
This is a cross-sectional study. Data were collected through a cohort involving 946 community-dwelling older people aged ≥ 60 with chronic musculoskeletal pain in Hong Kong. Selected independent variables were categorized into physical, psychological, and social domains. Physical variables included age, sex, body mass index (BMI), pain severity score, number of pain regions, the most painful site, and the number of comorbidities. Psychological variables included depression level measured using the 9-question Patient Health Questionnaire (PHQ-9), and anxiety level measured using the Generalized Anxiety Disorder Assessment (GAD-7). Social variables included living, marital, and social welfare recipient's status. The dependent variables comprised the index scores and the five dimensions of the EQ-5D descriptive system. Ordinal least squares (OLS) model and logistic regression model were used for data analysis.
The mean age of the participants was 67.1 (SD = 5.1), with 77.6% being female. Higher pain severity scores (beta (β) coefficient =-0.044, P |
doi_str_mv | 10.1186/s12877-024-04669-z |
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This is a cross-sectional study. Data were collected through a cohort involving 946 community-dwelling older people aged ≥ 60 with chronic musculoskeletal pain in Hong Kong. Selected independent variables were categorized into physical, psychological, and social domains. Physical variables included age, sex, body mass index (BMI), pain severity score, number of pain regions, the most painful site, and the number of comorbidities. Psychological variables included depression level measured using the 9-question Patient Health Questionnaire (PHQ-9), and anxiety level measured using the Generalized Anxiety Disorder Assessment (GAD-7). Social variables included living, marital, and social welfare recipient's status. The dependent variables comprised the index scores and the five dimensions of the EQ-5D descriptive system. Ordinal least squares (OLS) model and logistic regression model were used for data analysis.
The mean age of the participants was 67.1 (SD = 5.1), with 77.6% being female. Higher pain severity scores (beta (β) coefficient =-0.044, P < 0.001), depression scores (β=-0.007, P < 0.001) and higher anxiety scores (β=-0.01, P < 0.001) were associated with lower EQ-5D index scores. Specifically, knee pain (β=-0.061, P < 0.001) was significantly associated with lower EQ-5D index scores. Participants with higher pain severity and depression scores were more likely to report problems in most EQ-5D dimensions. Participants with anxiety primarily faced challenges related to mood, and those with knee pain were more likely to have problems with mobility and daily activities.
Among the selected determinants in our study, pain intensity, depression, anxiety, and knee pain were identified as key determinants associated with reduced HRQoL in older Chinese people with chronic musculoskeletal pain. Each of these determinants showed distinct associations with different dimensions of the EQ-5D, potentially informed resource allocation and the development of targeted interventions to improve the overall HRQoL of this specific population.</description><identifier>ISSN: 1471-2318</identifier><identifier>EISSN: 1471-2318</identifier><identifier>DOI: 10.1186/s12877-024-04669-z</identifier><identifier>PMID: 38297217</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Aged ; Analysis ; Anxiety ; Anxiety disorders ; Body mass index ; Chronic illnesses ; Chronic Musculoskeletal Pain ; Chronic pain ; Chronic Pain - diagnosis ; Chronic Pain - epidemiology ; Comorbidity ; Cross-Sectional Studies ; Disease ; East Asian People ; Female ; Generalized anxiety disorder ; Gerontology ; Health aspects ; Health Status ; Health surveys ; Health-related quality of life ; Humans ; Information management ; Informed consent ; Knee ; Male ; Mental depression ; Middle Aged ; Musculoskeletal Pain - diagnosis ; Musculoskeletal Pain - epidemiology ; Older people ; Patients ; Primary care ; Psychological aspects ; Quality of life ; Quality of Life - psychology ; Regression analysis ; Resource allocation ; Social networks ; Software ; Surveys and Questionnaires ; Variables ; Welfare</subject><ispartof>BMC geriatrics, 2024-01, Vol.24 (1), p.119-8, Article 119</ispartof><rights>2024. The Author(s).</rights><rights>COPYRIGHT 2024 BioMed Central Ltd.</rights><rights>2024. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c515t-e17a04e7d1e6ff8669cf8c88866c58c123284014037df0f77805edbd77cbdda73</cites><orcidid>0000-0003-0934-6385 ; 0000-0002-4717-7773 ; 0000-0003-3098-8673 ; 0009-0006-6740-0051</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10832201/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2925584334?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25752,27923,27924,37011,37012,44589,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38297217$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fong, Hugo Pak-Yiu</creatorcontrib><creatorcontrib>Choi, Shirley Yue-Kwan</creatorcontrib><creatorcontrib>Leung, Maria Kwan-Wa</creatorcontrib><creatorcontrib>Lo, Hermione Hin-Man</creatorcontrib><creatorcontrib>Wang, Bo</creatorcontrib><creatorcontrib>Wong, Samuel Yeung-Shan</creatorcontrib><creatorcontrib>Sit, Regina Wing-Shan</creatorcontrib><title>Determinants of health-related quality of life in older people with chronic musculoskeletal pain: a cross-sectional study</title><title>BMC geriatrics</title><addtitle>BMC Geriatr</addtitle><description>This study aimed to identify the significant physical, psychological, and social determinants associated with EuroQuol-5D (EQ-5D) among Chinese older people with chronic musculoskeletal pain, and to evaluate how these determinants affected the five dimensions of EQ-5D.
This is a cross-sectional study. Data were collected through a cohort involving 946 community-dwelling older people aged ≥ 60 with chronic musculoskeletal pain in Hong Kong. Selected independent variables were categorized into physical, psychological, and social domains. Physical variables included age, sex, body mass index (BMI), pain severity score, number of pain regions, the most painful site, and the number of comorbidities. Psychological variables included depression level measured using the 9-question Patient Health Questionnaire (PHQ-9), and anxiety level measured using the Generalized Anxiety Disorder Assessment (GAD-7). Social variables included living, marital, and social welfare recipient's status. The dependent variables comprised the index scores and the five dimensions of the EQ-5D descriptive system. Ordinal least squares (OLS) model and logistic regression model were used for data analysis.
The mean age of the participants was 67.1 (SD = 5.1), with 77.6% being female. Higher pain severity scores (beta (β) coefficient =-0.044, P < 0.001), depression scores (β=-0.007, P < 0.001) and higher anxiety scores (β=-0.01, P < 0.001) were associated with lower EQ-5D index scores. Specifically, knee pain (β=-0.061, P < 0.001) was significantly associated with lower EQ-5D index scores. Participants with higher pain severity and depression scores were more likely to report problems in most EQ-5D dimensions. Participants with anxiety primarily faced challenges related to mood, and those with knee pain were more likely to have problems with mobility and daily activities.
Among the selected determinants in our study, pain intensity, depression, anxiety, and knee pain were identified as key determinants associated with reduced HRQoL in older Chinese people with chronic musculoskeletal pain. Each of these determinants showed distinct associations with different dimensions of the EQ-5D, potentially informed resource allocation and the development of targeted interventions to improve the overall HRQoL of this specific population.</description><subject>Aged</subject><subject>Analysis</subject><subject>Anxiety</subject><subject>Anxiety disorders</subject><subject>Body mass index</subject><subject>Chronic illnesses</subject><subject>Chronic Musculoskeletal Pain</subject><subject>Chronic pain</subject><subject>Chronic Pain - diagnosis</subject><subject>Chronic Pain - epidemiology</subject><subject>Comorbidity</subject><subject>Cross-Sectional Studies</subject><subject>Disease</subject><subject>East Asian People</subject><subject>Female</subject><subject>Generalized anxiety disorder</subject><subject>Gerontology</subject><subject>Health aspects</subject><subject>Health Status</subject><subject>Health surveys</subject><subject>Health-related quality of life</subject><subject>Humans</subject><subject>Information management</subject><subject>Informed consent</subject><subject>Knee</subject><subject>Male</subject><subject>Mental depression</subject><subject>Middle Aged</subject><subject>Musculoskeletal Pain - diagnosis</subject><subject>Musculoskeletal Pain - epidemiology</subject><subject>Older people</subject><subject>Patients</subject><subject>Primary care</subject><subject>Psychological aspects</subject><subject>Quality of life</subject><subject>Quality of Life - psychology</subject><subject>Regression analysis</subject><subject>Resource allocation</subject><subject>Social networks</subject><subject>Software</subject><subject>Surveys and Questionnaires</subject><subject>Variables</subject><subject>Welfare</subject><issn>1471-2318</issn><issn>1471-2318</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNptUk1vEzEQXSEQLYU_wAFZ4sJli7927XBBVfmqVIkLnC2vPU4cvOvU9oLSX4-TlNIg5INHM--90cy8pnlJ8Dkhsn-bCZVCtJjyFvO-X7S3j5pTwgVpKSPy8YP4pHmW8xpjIiTtnzYnTNKFoEScNtsPUCCNftJTySg6tAIdyqpNEHQBi25mHXzZ7irBO0B-QjFYSGgDcRMA_fJlhcwqxckbNM7ZzCHmHxCg6IA22k_vkEYmxZzbDKb4ONV8LrPdPm-eOB0yvLj7z5rvnz5-u_zSXn_9fHV5cd2ajnSlBSI05iAsgd45Wcc0Thopa2Q6aQhlVHJMOGbCOuyEkLgDO1ghzGCtFuysuTro2qjXapP8qNNWRe3VPhHTUulUvAmgnKHSGc74YBxfOD5oIjoLrNNkINTqqvX-oLWZhxGsgakkHY5EjyuTX6ll_KkIloxSTKrCmzuFFG9myEWNPhsIQU8Q56zoghJCOtHvoK__ga7jnOr-9qiuk5wx_he11HUCP7lYG5udqLqo1yYLsZCsos7_g6rPwuhNnMD5mj8i0ANhf7sE7n5IgtXOfergPlXdp_buU7eV9Orheu4pf-zGfgOHSNc3</recordid><startdate>20240131</startdate><enddate>20240131</enddate><creator>Fong, Hugo Pak-Yiu</creator><creator>Choi, Shirley Yue-Kwan</creator><creator>Leung, Maria Kwan-Wa</creator><creator>Lo, Hermione Hin-Man</creator><creator>Wang, Bo</creator><creator>Wong, Samuel Yeung-Shan</creator><creator>Sit, Regina Wing-Shan</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><general>BMC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-0934-6385</orcidid><orcidid>https://orcid.org/0000-0002-4717-7773</orcidid><orcidid>https://orcid.org/0000-0003-3098-8673</orcidid><orcidid>https://orcid.org/0009-0006-6740-0051</orcidid></search><sort><creationdate>20240131</creationdate><title>Determinants of health-related quality of life in older people with chronic musculoskeletal pain: a cross-sectional study</title><author>Fong, Hugo Pak-Yiu ; Choi, Shirley Yue-Kwan ; Leung, Maria Kwan-Wa ; Lo, Hermione Hin-Man ; Wang, Bo ; Wong, Samuel Yeung-Shan ; Sit, Regina Wing-Shan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c515t-e17a04e7d1e6ff8669cf8c88866c58c123284014037df0f77805edbd77cbdda73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Aged</topic><topic>Analysis</topic><topic>Anxiety</topic><topic>Anxiety disorders</topic><topic>Body mass index</topic><topic>Chronic illnesses</topic><topic>Chronic Musculoskeletal Pain</topic><topic>Chronic pain</topic><topic>Chronic Pain - diagnosis</topic><topic>Chronic Pain - epidemiology</topic><topic>Comorbidity</topic><topic>Cross-Sectional Studies</topic><topic>Disease</topic><topic>East Asian People</topic><topic>Female</topic><topic>Generalized anxiety disorder</topic><topic>Gerontology</topic><topic>Health aspects</topic><topic>Health Status</topic><topic>Health surveys</topic><topic>Health-related quality of life</topic><topic>Humans</topic><topic>Information management</topic><topic>Informed consent</topic><topic>Knee</topic><topic>Male</topic><topic>Mental depression</topic><topic>Middle Aged</topic><topic>Musculoskeletal Pain - diagnosis</topic><topic>Musculoskeletal Pain - epidemiology</topic><topic>Older people</topic><topic>Patients</topic><topic>Primary care</topic><topic>Psychological aspects</topic><topic>Quality of life</topic><topic>Quality of Life - psychology</topic><topic>Regression analysis</topic><topic>Resource allocation</topic><topic>Social networks</topic><topic>Software</topic><topic>Surveys and Questionnaires</topic><topic>Variables</topic><topic>Welfare</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fong, Hugo Pak-Yiu</creatorcontrib><creatorcontrib>Choi, Shirley Yue-Kwan</creatorcontrib><creatorcontrib>Leung, Maria Kwan-Wa</creatorcontrib><creatorcontrib>Lo, Hermione Hin-Man</creatorcontrib><creatorcontrib>Wang, Bo</creatorcontrib><creatorcontrib>Wong, Samuel Yeung-Shan</creatorcontrib><creatorcontrib>Sit, Regina Wing-Shan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Publicly Available Content (ProQuest)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>BMC geriatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fong, Hugo Pak-Yiu</au><au>Choi, Shirley Yue-Kwan</au><au>Leung, Maria Kwan-Wa</au><au>Lo, Hermione Hin-Man</au><au>Wang, Bo</au><au>Wong, Samuel Yeung-Shan</au><au>Sit, Regina Wing-Shan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Determinants of health-related quality of life in older people with chronic musculoskeletal pain: a cross-sectional study</atitle><jtitle>BMC geriatrics</jtitle><addtitle>BMC Geriatr</addtitle><date>2024-01-31</date><risdate>2024</risdate><volume>24</volume><issue>1</issue><spage>119</spage><epage>8</epage><pages>119-8</pages><artnum>119</artnum><issn>1471-2318</issn><eissn>1471-2318</eissn><abstract>This study aimed to identify the significant physical, psychological, and social determinants associated with EuroQuol-5D (EQ-5D) among Chinese older people with chronic musculoskeletal pain, and to evaluate how these determinants affected the five dimensions of EQ-5D.
This is a cross-sectional study. Data were collected through a cohort involving 946 community-dwelling older people aged ≥ 60 with chronic musculoskeletal pain in Hong Kong. Selected independent variables were categorized into physical, psychological, and social domains. Physical variables included age, sex, body mass index (BMI), pain severity score, number of pain regions, the most painful site, and the number of comorbidities. Psychological variables included depression level measured using the 9-question Patient Health Questionnaire (PHQ-9), and anxiety level measured using the Generalized Anxiety Disorder Assessment (GAD-7). Social variables included living, marital, and social welfare recipient's status. The dependent variables comprised the index scores and the five dimensions of the EQ-5D descriptive system. Ordinal least squares (OLS) model and logistic regression model were used for data analysis.
The mean age of the participants was 67.1 (SD = 5.1), with 77.6% being female. Higher pain severity scores (beta (β) coefficient =-0.044, P < 0.001), depression scores (β=-0.007, P < 0.001) and higher anxiety scores (β=-0.01, P < 0.001) were associated with lower EQ-5D index scores. Specifically, knee pain (β=-0.061, P < 0.001) was significantly associated with lower EQ-5D index scores. Participants with higher pain severity and depression scores were more likely to report problems in most EQ-5D dimensions. Participants with anxiety primarily faced challenges related to mood, and those with knee pain were more likely to have problems with mobility and daily activities.
Among the selected determinants in our study, pain intensity, depression, anxiety, and knee pain were identified as key determinants associated with reduced HRQoL in older Chinese people with chronic musculoskeletal pain. Each of these determinants showed distinct associations with different dimensions of the EQ-5D, potentially informed resource allocation and the development of targeted interventions to improve the overall HRQoL of this specific population.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>38297217</pmid><doi>10.1186/s12877-024-04669-z</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0003-0934-6385</orcidid><orcidid>https://orcid.org/0000-0002-4717-7773</orcidid><orcidid>https://orcid.org/0000-0003-3098-8673</orcidid><orcidid>https://orcid.org/0009-0006-6740-0051</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Aged Analysis Anxiety Anxiety disorders Body mass index Chronic illnesses Chronic Musculoskeletal Pain Chronic pain Chronic Pain - diagnosis Chronic Pain - epidemiology Comorbidity Cross-Sectional Studies Disease East Asian People Female Generalized anxiety disorder Gerontology Health aspects Health Status Health surveys Health-related quality of life Humans Information management Informed consent Knee Male Mental depression Middle Aged Musculoskeletal Pain - diagnosis Musculoskeletal Pain - epidemiology Older people Patients Primary care Psychological aspects Quality of life Quality of Life - psychology Regression analysis Resource allocation Social networks Software Surveys and Questionnaires Variables Welfare |
title | Determinants of health-related quality of life in older people with chronic musculoskeletal pain: a cross-sectional study |
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