Pairing off: a bottom‐up approach to the human gut microbiome

The human gut microbiome has been implicated in a variety of health outcomes, and extensive research has aimed to understand its composition and function, primarily via metagenomic analyses. An examination of how the microbiome develops and interacts through interspecies competition and cooperation...

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Bibliographic Details
Published in:Molecular systems biology 2018-06, Vol.14 (6), p.e8425-n/a
Main Authors: Abreu, Clare, Ortiz Lopez, Anthony, Gore, Jeff
Format: Article
Language:English
Subjects:
Digestive system
EMBO23
EMBO33
EMBO41
Gastrointestinal Microbiome
Humans
Intestinal microflora
Microbial Interactions
Microbiomes
Microbiota
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Summary:The human gut microbiome has been implicated in a variety of health outcomes, and extensive research has aimed to understand its composition and function, primarily via metagenomic analyses. An examination of how the microbiome develops and interacts through interspecies competition and cooperation has been lacking so far. In their recent work, Venturelli et al ( 2018 ) build a synthetic gut community and accurately predict its dynamics with a simple network of pairwise interactions. Graphical Abstract Analyses of how the gut microbiome develops and evolves through interspecies competition and cooperation have been lacking. In their recent work, Venturelli et al ( 2018 ) build a synthetic gut bacterial community and predict its dynamics with a simple network of pairwise interactions.
ISSN:1744-4292
1744-4292
DOI:10.15252/msb.20188425