Prevalence and Associated Factors of Paroxysmal Atrial Fibrillation and Atrial Arrhythmias During Hospitalizations for Exacerbation of COPD

• Published in: International journal of chronic obstructive pulmonary disease 2024-09, Vol.19, p.1989-2000
• Main Authors: Nguyen, Hieu Lan, Nguyen, Thang Duy, Phan, Phuong Thu
• Format: Article
• Language: English
• Subjects: Age Factors; Aged; Aged, 80 and over; Arrhythmia; associated factor; atrial arrhythmias; Atrial fibrillation; Atrial Fibrillation - diagnosis; Atrial Fibrillation - epidemiology; Atrial Fibrillation - physiopathology; Atrial Fibrillation - therapy; Atrial Premature Complexes - diagnosis; Atrial Premature Complexes - epidemiology; Atrial Premature Complexes - physiopathology; chronic obstructive pulmonary disease; Complications and side effects; Disease Progression; Electrocardiography, Ambulatory; Female; Hospitalization - statistics & numerical data; Humans; Lung diseases, Obstructive; Male; Middle Aged; Original Research; p wave dispersion; Prevalence; Prospective Studies; Pulmonary Disease, Chronic Obstructive - diagnosis; Pulmonary Disease, Chronic Obstructive - epidemiology; Pulmonary Disease, Chronic Obstructive - physiopathology; Pulmonary Disease, Chronic Obstructive - therapy; Risk Assessment; Risk Factors; Vietnam - epidemiology
• ISSN: 1178-2005; 1176-9106; 1178-2005
• DOI: 10.2147/COPD.S473289

This study aimed to investigate the proportion and risk factors of paroxysmal atrial fibrillation (AF) and atrial arrhythmias (AA) in patients hospitalized for acute exacerbation of chronic obstructive pulmonary disease (AECOPD) in Vietnam. A prospective observational study was conducted at two major hospitals in Hanoi, Vietnam, from January 2022 to January 2023. A total of 197 AECOPD patients were recruited. ECG and 24-hour Holter ECG were used to diagnose paroxysmal AF and AA. The prevalence of paroxysmal AF and AA were 15.2% and 72.6%, respectively. Factors associated with a higher likelihood of paroxysmal AF included aging 75 years old and above (aOR = 3.15; 95% CI: 1.28 to 8.48), Premature atrial complex (PAC) with 500 or more (aOR = 3.81; 95% CI: 1.48 to 10.97) and severity of COPD as group C and D (aOR = 3.41; 95% CI: 1.28 to 10.50). For AA, aging 75 years old and above (aOR = 2.25; 95% CI: 1.28 to 5.20), smoking (aOR = 2.10; 95% CI: 1.07 to 4.23) and P wave dispersion (PWD) with 40 milliseconds or more (aOR = 3.04; 95% CI: 1.54 to 6.19) were associated with a higher likelihood of AA. Overall, our findings highlight the associated factors with the paroxysmal AF and AA among AECOPD patients. This underscores the importance of a multifaceted approach to risk assessment and management in this vulnerable population, focusing not only on respiratory symptoms but also on comprehensive cardiovascular evaluation and intervention.