A survey of reasons for continuing warfarin therapy in the era of direct oral anticoagulants in Japanese patients with atrial fibrillation: the SELECT study

Although warfarin has historically been the standard of care for preventing ischemic stroke in patients with nonvalvular atrial fibrillation (NVAF), the use of direct oral anticoagulants (DOACs) is rapidly increasing. In this study, we examined the demographic and clinical characteristics of patient...

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Bibliographic Details
Published in:Patient preference and adherence 2018-01, Vol.12, p.135-143
Main Authors: Ikeda, Takanori, Yasaka, Masahiro, Kida, Makoto, Imura, Miki
Format: Article
Language:English
Subjects:
anticoagulant
Anticoagulants
Apixaban
Atrial fibrillation
Care and treatment
Fibrillation
Ischemia
Japanese patients
Medical records
Medical research
nonvalvular atrial fibrillation
Original Research
Patient satisfaction
Rivaroxaban
Stroke
Warfarin
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Summary:Although warfarin has historically been the standard of care for preventing ischemic stroke in patients with nonvalvular atrial fibrillation (NVAF), the use of direct oral anticoagulants (DOACs) is rapidly increasing. In this study, we examined the demographic and clinical characteristics of patients continuing warfarin therapy and investigated reasons for warfarin continuation. Each study site consecutively registered 10 patients with NVAF who had been taking warfarin for at least 12 months. Demographic and clinical characteristics and international normalized ratio (INR) values were collected from medical records. Physicians responded to questionnaires exploring reasons for continuing warfarin therapy. Overall, 313 patients treated with warfarin were registered at 33 sites. Mean ± SD age was 76.4±9.6 years; 62.9% of patients were male. The proportion of patients with INR values in the therapeutic range was 74.6% and 48.8% among patients aged ≥70 years and
ISSN:1177-889X
1177-889X
DOI:10.2147/PPA.S152584