Aryl Methyl Ketones: Versatile Synthons in the Synthesis of Heterocyclic Compounds

Abstract The synthesis of aromatic heterocycles has attracted substantial attention due to the abundance of these heterocycles in drug molecules, natural products, and other compounds of biological interest. Accordingly, there is a demand for straightforward synthetic protocols toward such compounds...

Full description

Saved in:
Bibliographic Details
Published in:SynOpen (2017) 2022-05, Vol.6 (2), p.110-131
Main Authors: Mohammed, Shabber, West, Jason S., Mitton-Fry, Mark J.
Format: Article
Language:English
Subjects:
aromatic heterocycles
fused bicycles
fused polyheterocycles
fused tricycles
Graphical Review
iodine
ketones
metal-free
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract The synthesis of aromatic heterocycles has attracted substantial attention due to the abundance of these heterocycles in drug molecules, natural products, and other compounds of biological interest. Accordingly, there is a demand for straightforward synthetic protocols toward such compounds using readily available starting materials. In the past decade, there have been substantial developments in heterocycle synthesis, especially in metal-catalyzed and iodine-assisted approaches. This graphical review focuses on notable reactions from the past decade using aryl and heteroaryl methyl ketones as starting materials, including representative reaction mechanisms.
ISSN:2509-9396
2509-9396
DOI:10.1055/a-1826-2852