Association of retinal thickness and optic disc-to-fovea angle to axial length of young healthy eyes

• Published in: Clinical ophthalmology (Auckland, N.Z.) N.Z.), 2015-01, Vol.9 (default), p.2235-2241
• Main Authors: Yamashita, Takehiro, Sakamoto, Taiji, Terasaki, Hiroto, Tanaka, Minoru, Kii, Yuya, Uchino, Eisuke, Hisatomi, Toshio, Nakao, Kumiko
• Format: Article
• Language: English
• Subjects: Analysis; Family medical history; Hospitals; Optics; Original Research; Physiological aspects; Registration; Retina; Studies; Thickness measurement; Visual acuity
• ISSN: 1177-5467; 1177-5483; 1177-5483
• DOI: 10.2147/OPTH.S93197

To determine the relationship between the axial length (AL) and the retinal thickness in the posterior pole and to the optic disc-to-fovea (ODF) angle of healthy eyes. A prospective, observational cross-sectional study (registration number, UMIN000006040) of 64 healthy right eyes (mean age 26.0±4.5 years) was performed. The thickness of the 64 areas within the central 24° area were measured in the Spectralis spectral domain-optical coherent tomographic images obtained by posterior pole scans. Each area was 3°×3°. The ODF angle was measured in each fundus photograph. The relationships between the AL and the retinal thickness of each of the 64 areas and the ODF angle were investigated by linear regression analyses. The mean AL was 25.0±1.3 mm and the mean ODF angle was 17.2°±1.0°. The average retinal thickness of the four areas around the fovea was constant and not significantly correlated with the AL. However, the retinal thicknesses of 54 of the other 60 areas were significantly and negatively correlated with the AL (R=-0.25 to -0.56, P