Cyclodextrin Inclusion Complexes and Their Application in Food Safety Analysis: Recent Developments and Future Prospects

Food safety issues are a major threat to public health and have attracted much attention. Therefore, exploring accurate, efficient, sensitive, and economical detection methods is necessary to ensure consumers' health. In this regard, cyclodextrins (CDs) are promising candidates because they are...

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Bibliographic Details
Published in:Foods 2022-11, Vol.11 (23), p.3871
Main Authors: Zhou, Jiaojiao, Jia, Jilai, He, Jiangling, Li, Jinjie, Cai, Jie
Format: Article
Language:English
Subjects:
Agricultural production
Amino acids
Cadmium
Chemoreception
Cyclodextrin
cyclodextrin inclusion complexes
Cyclodextrins
Electrostatic properties
Enzymes
Food industry
Food safety
Food science
Food technology
Glucose
Heavy metals
Hydrogen bonding
Hydrophobicity
Inclusion complexes
Microorganisms
Molecular weight
NMR
Nuclear magnetic resonance
Oxidation
Properties
Public health
Review
Ring structures
Safety
Target detection
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Summary:Food safety issues are a major threat to public health and have attracted much attention. Therefore, exploring accurate, efficient, sensitive, and economical detection methods is necessary to ensure consumers' health. In this regard, cyclodextrins (CDs) are promising candidates because they are nontoxic and noncaloric. The main body of CDs is a ring structure with hydrophobic cavity and hydrophilic exterior wall. Due to the above characteristics, CDs can encapsulate small guest molecules into their cavities, enhance their stability, avoid agglomeration and oxidation, and, at the same time, interact through hydrogen bonding and electrostatic interactions. Additionally, they can selectively capture the target molecules to be detected and improve the sensitivity of food detection. This review highlights recent advances in CD inclusion technology in food safety analysis, covering various applications from small molecule and heavy metal sensing to amino acid and microbial sensing. Finally, challenges and prospects for CDs and their derivatives are presented. The current review can provide a reference and guidance for current research on CDs in the food industry and may inspire breakthroughs in this field.
ISSN:2304-8158
2304-8158
DOI:10.3390/foods11233871