Hypervirulent Klebsiella pneumoniae infection in a woman with a CDH1 gene mutation

The CDH1 gene, which encodes E-cadherin, may be associated with cancer when mutated, but the significance of mutations in the context of infection is unknown. In this report, we describe a case of disseminated hypervirulent Klebsiella pneumoniae infection in a 49 year old Caucasian woman with a docu...

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Bibliographic Details
Published in:IDCases 2021-01, Vol.23, p.e01000, Article e01000
Main Authors: Kaye, Alexander J., Chin, Adam T., Liang, Michelle C., Viau Colindres, Roberto
Format: Article
Language:English
Subjects:
Cadherin-1
Case Report
Disease susceptibility
Host-pathogen interactions
Klebsiella pneumoniae/pathogenicity
Suppurative
Uveitis
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Summary:The CDH1 gene, which encodes E-cadherin, may be associated with cancer when mutated, but the significance of mutations in the context of infection is unknown. In this report, we describe a case of disseminated hypervirulent Klebsiella pneumoniae infection in a 49 year old Caucasian woman with a documented CDH1 mutation.
ISSN:2214-2509
2214-2509
DOI:10.1016/j.idcr.2020.e01000