Human herpesvirus 8 genotype E in patients with Kaposi sarcoma, Peru

To determine human herpesvirus 8 (HHV-8) K1 genotypes in patients with Kaposi sarcoma (KS) from Peru, we characterized HHV-8 in 25 KS biopsy samples. Our findings of 8 A, 1 B, 14 C, and 2 E subtypes showed high HHV-8 diversity in these patients and association between E genotype and KS development.

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Bibliographic Details
Published in:Emerging infectious diseases 2010-09, Vol.16 (9), p.1459-1462
Main Authors: Cassar, Olivier, Blondot, Marie Lise, Mohanna, Salim, Jouvion, Gregory, Bravo, Francisco, Maco, Vicente, Duprez, Renan, Huerre, Michel, Gotuzzo, Eduardo, Gessain, Antoine
Format: Article
Language:English
Subjects:
AIDS-Related Opportunistic Infections - pathology
AIDS-Related Opportunistic Infections - virology
Care and treatment
Dispatch
DNA, Viral - genetics
epidemiology
Genes, Viral
Genetic aspects
Genotype
Health aspects
Herpesvirus 8, Human - classification
Herpesvirus 8, Human - genetics
HHV-8
Human herpesvirus 8
Humans
Infection
Kaposi sarcoma
Kaposi's sarcoma
Life Sciences
Male
Microbiology and Parasitology
Middle Aged
molecular epidemiology
Molecular Sequence Data
Peru
Phylogeny
Sarcoma, Kaposi - pathology
Sarcoma, Kaposi - virology
Young Adult
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Description
Summary:To determine human herpesvirus 8 (HHV-8) K1 genotypes in patients with Kaposi sarcoma (KS) from Peru, we characterized HHV-8 in 25 KS biopsy samples. Our findings of 8 A, 1 B, 14 C, and 2 E subtypes showed high HHV-8 diversity in these patients and association between E genotype and KS development.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid1609.100381