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Incidence of congenital toxoplasmosis in the City of Belém, State of Pará, Northern Brazil, determined by a neonatal screening program: preliminary results

The aim of this study was to determinate the incidence of congenital toxoplasmosis among a group of newborns (NBs) from Belém using neonatal screening. Among the 6,000 newborns referred for investigation of genetic and metabolic diseases, 1,000 were selected for screening for congenital toxoplasmosi...

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Published in:Revista da Sociedade Brasileira de Medicina Tropical 2012-02, Vol.45 (1), p.122-124
Main Authors: Bichara, Cléa Nazaré Carneiro, Canto, Giselle Acácia de Cristo, Tostes, Camila de Lima, Freitas, Jofre Jacob da Silva, Carmo, Ediclei Lima do, Póvoa, Marinete Marins, Silveira, Eliete da Costa
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container_title Revista da Sociedade Brasileira de Medicina Tropical
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creator Bichara, Cléa Nazaré Carneiro
Canto, Giselle Acácia de Cristo
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Póvoa, Marinete Marins
Silveira, Eliete da Costa
description The aim of this study was to determinate the incidence of congenital toxoplasmosis among a group of newborns (NBs) from Belém using neonatal screening. Among the 6,000 newborns referred for investigation of genetic and metabolic diseases, 1,000 were selected for screening for congenital toxoplasmosis by determining the amount of IgM in the eluates of blood collected on filter paper. Positive tests were confirmed using paired serology of the NB and his mother. Out of the 1,000 NBs assessed, one had a positive screening result that was confirmed by paired serology. The incidence of congenital toxoplasmosis in Belém was 10/10,000 live NBs.
doi_str_mv 10.1590/S0037-86822012000100024
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subjects Antibodies, Protozoan - blood
Brazil - epidemiology
Congenital diseases
Enzyme-Linked Immunosorbent Assay
Female
Humans
Immunoglobulin G - blood
Immunoglobulin M - blood
Incidence
Incidência
Infant, Newborn
Medical screening
Metabolic disorders
Neonatal care
Neonatal Screening
Toxoplasma - immunology
Toxoplasmose congênita
Toxoplasmosis
Toxoplasmosis, Congenital - diagnosis
Toxoplasmosis, Congenital - epidemiology
Triagem neonatal
TROPICAL MEDICINE
title Incidence of congenital toxoplasmosis in the City of Belém, State of Pará, Northern Brazil, determined by a neonatal screening program: preliminary results
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