Pulmonary Metastasis of a Gigantic Cystosarcoma Phyllodes of the Breast

The biopsy of the left breast was performed under ultrasound guidance, and the pathological finding indicated a malignant tumor of mesenchymal origin, otherwise known as a gigantic cystosarcoma phyllodes [Figure 1]e. Immunohistochemical analysis showed local pan-cytokeratin (+), vimentin (+), P63 (-...

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Bibliographic Details
Published in:Chinese medical journal 2018-03, Vol.131 (6), p.751-752
Main Authors: Gao, Yan-Hong, Xiang, Hui-Juan, Zhu, Jian, Duan, Yun, Zhou, Pei
Format: Article
Language:English
Subjects:
Breast cancer
Cancer metastasis
Care and treatment
Case studies
Complications and side effects
Correspondence
Development and progression
Lung cancer
Metastasis
Phyllodes tumor
Tumors
Ultrasonic imaging
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Summary:The biopsy of the left breast was performed under ultrasound guidance, and the pathological finding indicated a malignant tumor of mesenchymal origin, otherwise known as a gigantic cystosarcoma phyllodes [Figure 1]e. Immunohistochemical analysis showed local pan-cytokeratin (+), vimentin (+), P63 (-), cytokeratin 516 (-), CD34 (+), few scattering in the CD68 (+), Ki-67: 50%, the local smooth muscle actin (+), the local S-100 (+), estrogen receptor (-), progesterone receptor (-), E-cadherin (-), dosmin (-), actin (+), the local CD10 (+), and CD117 (-). The mass could increase rapidly during a short time, and the enlarged mass could occupy most of the breast or even the whole breast. Because cystosarcoma phyllodes of the breast often has no indirect signs of breast malignancy, it is often misdiagnosed as breast fibroadenoma or giant fibroadenoma. [3] Since cystosarcoma phyllodes of the breast does not have a true capsule and is highly invasive, it is not easy to excise. [...]most researchers recommend radical mastectomy, including total resection of the ectopectoralis fascia.
ISSN:0366-6999
2542-5641
DOI:10.4103/0366-6999.226898