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Factors Affecting Adherence to Co-Trimoxazole Preventive Therapy in HIV/AIDS Patients Attending an Antiretroviral Therapy Clinic in Ethiopia University Hospital: A Cross-Sectional Study
Purpose: This study aimed to assess the factors that affect adherence to co-trimoxazole preventive therapy (CPT) among human immunodeficiency virus (HIV)-positive adults in an antiretroviral therapy (ART) clinic at the University of Gondar Compressive Specialized Teaching Hospital (UOGCSTH). Methods...
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Published in: | Patient preference and adherence 2020-01, Vol.14, p.881-890 |
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description | Purpose: This study aimed to assess the factors that affect adherence to co-trimoxazole preventive therapy (CPT) among human immunodeficiency virus (HIV)-positive adults in an antiretroviral therapy (ART) clinic at the University of Gondar Compressive Specialized Teaching Hospital (UOGCSTH). Methods: A hospital-based cross-sectional study was conducted from March 1 to April 30, 2018, at the ART clinic at UOGCSTH. Data were collected using face-to-face interviews with pretested and standard questionnaires. Binary and multivariable logistic regression analyses were used to assess the association between different variables. P< 0.05 was used to declare the association. Results: The prevalence of adherence to CPT by self-reporting measurement was 205 (67.8%). Factors such as level of education, taking street drugs (alcohol and khat), spouse knowledge about clients on CPT, knowledge of the benefit of CPT, duration of CPT, missed dose, got proper information on how to take CPT, and counseling done on refill were found to be significantly associated with adherence to CPT. Conclusion and Recommendations: The overall adherence to CPT was fair in our study. To improve the adherence, continuous education and counseling, giving group service support for clients and having a separate counseling room are some of the possible solutions. |
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Methods: A hospital-based cross-sectional study was conducted from March 1 to April 30, 2018, at the ART clinic at UOGCSTH. Data were collected using face-to-face interviews with pretested and standard questionnaires. Binary and multivariable logistic regression analyses were used to assess the association between different variables. P< 0.05 was used to declare the association. Results: The prevalence of adherence to CPT by self-reporting measurement was 205 (67.8%). Factors such as level of education, taking street drugs (alcohol and khat), spouse knowledge about clients on CPT, knowledge of the benefit of CPT, duration of CPT, missed dose, got proper information on how to take CPT, and counseling done on refill were found to be significantly associated with adherence to CPT. Conclusion and Recommendations: The overall adherence to CPT was fair in our study. To improve the adherence, continuous education and counseling, giving group service support for clients and having a separate counseling room are some of the possible solutions.</description><identifier>ISSN: 1177-889X</identifier><identifier>EISSN: 1177-889X</identifier><identifier>DOI: 10.2147/PPA.S252805</identifier><language>eng</language><publisher>Auckland: Taylor & Francis Ltd</publisher><subject>Acquired immune deficiency syndrome ; adherence ; AIDS ; Antibiotics ; Antiretroviral drugs ; cotrimoxazole preventive therapy ; Cross-sectional studies ; Disease prevention ; ethiopia ; factors ; Health behavior ; HIV ; hiv/aids ; Human immunodeficiency virus ; Patient compliance ; Socioeconomic factors</subject><ispartof>Patient preference and adherence, 2020-01, Vol.14, p.881-890</ispartof><rights>2020. This work is licensed under https://creativecommons.org/licenses/by-nc/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c364t-5c45f6e1aca3425f9591d42a8410cdf0b2e7fd20733e824f37feb51942e00cb83</citedby><cites>FETCH-LOGICAL-c364t-5c45f6e1aca3425f9591d42a8410cdf0b2e7fd20733e824f37feb51942e00cb83</cites><orcidid>0000-0002-2650-8668</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2414104647/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2414104647?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,25753,27924,27925,37012,44590,75126</link.rule.ids></links><search><creatorcontrib>Mekonnen, Gashaw Binega</creatorcontrib><creatorcontrib>Addis, Surafel Ashenafi</creatorcontrib><title>Factors Affecting Adherence to Co-Trimoxazole Preventive Therapy in HIV/AIDS Patients Attending an Antiretroviral Therapy Clinic in Ethiopia University Hospital: A Cross-Sectional Study</title><title>Patient preference and adherence</title><description>Purpose: This study aimed to assess the factors that affect adherence to co-trimoxazole preventive therapy (CPT) among human immunodeficiency virus (HIV)-positive adults in an antiretroviral therapy (ART) clinic at the University of Gondar Compressive Specialized Teaching Hospital (UOGCSTH). Methods: A hospital-based cross-sectional study was conducted from March 1 to April 30, 2018, at the ART clinic at UOGCSTH. Data were collected using face-to-face interviews with pretested and standard questionnaires. Binary and multivariable logistic regression analyses were used to assess the association between different variables. P< 0.05 was used to declare the association. Results: The prevalence of adherence to CPT by self-reporting measurement was 205 (67.8%). Factors such as level of education, taking street drugs (alcohol and khat), spouse knowledge about clients on CPT, knowledge of the benefit of CPT, duration of CPT, missed dose, got proper information on how to take CPT, and counseling done on refill were found to be significantly associated with adherence to CPT. Conclusion and Recommendations: The overall adherence to CPT was fair in our study. To improve the adherence, continuous education and counseling, giving group service support for clients and having a separate counseling room are some of the possible solutions.</description><subject>Acquired immune deficiency syndrome</subject><subject>adherence</subject><subject>AIDS</subject><subject>Antibiotics</subject><subject>Antiretroviral drugs</subject><subject>cotrimoxazole preventive therapy</subject><subject>Cross-sectional studies</subject><subject>Disease prevention</subject><subject>ethiopia</subject><subject>factors</subject><subject>Health behavior</subject><subject>HIV</subject><subject>hiv/aids</subject><subject>Human immunodeficiency virus</subject><subject>Patient compliance</subject><subject>Socioeconomic factors</subject><issn>1177-889X</issn><issn>1177-889X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNpNkdGO1CAUhhujievqlS9A4qXpLlBoi3dN3XUm2cRJZtZ4Ryg97DKpUIGZOL6Zbyd1Nhu5gcB_vvMf_qJ4T_AVJay53my6qy3ltMX8RXFBSNOUbSu-v_zv_Lp4E-Me47qqKbko_twqnXyIqDMGdLLuAXXjIwRwGlDyqPflLtgf_pf67SdAmwBHcMkeAe2ySs0nZB1arb9dd-vPW7RRyebnTEsJ3LjQlENdLgiQgj_aoKbnwn6yzuql_iY9Wj9bhe5dJodo0wmtfJxtUtMn1KE--BjL7eLPu0zYpsN4elu8MmqK8O5pvyzub292_aq8-_pl3Xd3pa5qlkquGTc1EKVVxSg3ggsyMqpaRrAeDR4oNGakuKkqaCkzVWNg4EQwChjroa0ui_WZO3q1l3P-DBVO0isr_1348CBVSFZPII1pNR_z4qJijAsxiFELki2oZsidMuvDmTUH__MAMcm9P4Q8UpSUkeyI1azJqo9nlV7mDmCeuxIsl5xlzlk-5Vz9BbGsnc8</recordid><startdate>20200101</startdate><enddate>20200101</enddate><creator>Mekonnen, Gashaw Binega</creator><creator>Addis, Surafel Ashenafi</creator><general>Taylor & Francis Ltd</general><general>Dove Medical Press</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7XB</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>KB0</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-2650-8668</orcidid></search><sort><creationdate>20200101</creationdate><title>Factors Affecting Adherence to Co-Trimoxazole Preventive Therapy in HIV/AIDS Patients Attending an Antiretroviral Therapy Clinic in Ethiopia University Hospital: A Cross-Sectional Study</title><author>Mekonnen, Gashaw Binega ; Addis, Surafel Ashenafi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c364t-5c45f6e1aca3425f9591d42a8410cdf0b2e7fd20733e824f37feb51942e00cb83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Acquired immune deficiency syndrome</topic><topic>adherence</topic><topic>AIDS</topic><topic>Antibiotics</topic><topic>Antiretroviral drugs</topic><topic>cotrimoxazole preventive therapy</topic><topic>Cross-sectional studies</topic><topic>Disease prevention</topic><topic>ethiopia</topic><topic>factors</topic><topic>Health behavior</topic><topic>HIV</topic><topic>hiv/aids</topic><topic>Human immunodeficiency virus</topic><topic>Patient compliance</topic><topic>Socioeconomic factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mekonnen, Gashaw Binega</creatorcontrib><creatorcontrib>Addis, Surafel Ashenafi</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Nursing and Allied Health Source</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest - Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Patient preference and adherence</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mekonnen, Gashaw Binega</au><au>Addis, Surafel Ashenafi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Factors Affecting Adherence to Co-Trimoxazole Preventive Therapy in HIV/AIDS Patients Attending an Antiretroviral Therapy Clinic in Ethiopia University Hospital: A Cross-Sectional Study</atitle><jtitle>Patient preference and adherence</jtitle><date>2020-01-01</date><risdate>2020</risdate><volume>14</volume><spage>881</spage><epage>890</epage><pages>881-890</pages><issn>1177-889X</issn><eissn>1177-889X</eissn><abstract>Purpose: This study aimed to assess the factors that affect adherence to co-trimoxazole preventive therapy (CPT) among human immunodeficiency virus (HIV)-positive adults in an antiretroviral therapy (ART) clinic at the University of Gondar Compressive Specialized Teaching Hospital (UOGCSTH). Methods: A hospital-based cross-sectional study was conducted from March 1 to April 30, 2018, at the ART clinic at UOGCSTH. Data were collected using face-to-face interviews with pretested and standard questionnaires. Binary and multivariable logistic regression analyses were used to assess the association between different variables. P< 0.05 was used to declare the association. Results: The prevalence of adherence to CPT by self-reporting measurement was 205 (67.8%). Factors such as level of education, taking street drugs (alcohol and khat), spouse knowledge about clients on CPT, knowledge of the benefit of CPT, duration of CPT, missed dose, got proper information on how to take CPT, and counseling done on refill were found to be significantly associated with adherence to CPT. Conclusion and Recommendations: The overall adherence to CPT was fair in our study. 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subjects | Acquired immune deficiency syndrome adherence AIDS Antibiotics Antiretroviral drugs cotrimoxazole preventive therapy Cross-sectional studies Disease prevention ethiopia factors Health behavior HIV hiv/aids Human immunodeficiency virus Patient compliance Socioeconomic factors |
title | Factors Affecting Adherence to Co-Trimoxazole Preventive Therapy in HIV/AIDS Patients Attending an Antiretroviral Therapy Clinic in Ethiopia University Hospital: A Cross-Sectional Study |
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