Web search volume as a near-real-time complementary surveillance tool of tick-borne encephalitis (TBE) in Italy

• Published in: Ticks and tick-borne diseases 2024-05, Vol.15 (3), p.102332-102332, Article 102332
• Main Authors: Domnich, Alexander, Ferrari, Allegra, Ogliastro, Matilde, Orsi, Andrea, Icardi, Giancarlo
• Format: Article
• Language: English
• Subjects: Google Trends; Infoveillance; Internet; Italy; monitoring; prediction; summer; TBE; Tick-borne encephalitis; time series analysis
• ISSN: 1877-959X; 1877-9603
• DOI: 10.1016/j.ttbdis.2024.102332

The Internet is an important gateway for accessing health-related information, and data generated through web queries have been increasingly used as a complementary source for monitoring and forecasting of infectious diseases and they may partially address the issue of underreporting. In this study, we assessed whether tick-borne encephalitis (TBE)-related Internet search volume may be useful as a complementary tool for TBE surveillance in Italy. Monthly Google Trends (GT) data for TBE-related information were extracted for the period between January 2017 and September 2022, corresponding to the available time series of TBE notifications in Italy. Time series modeling was performed by applying seasonal autoregressive integrated moving average (SARIMA) models with or without GT data. The search terms relative to tick bites reflected best the observed temporal distribution of TBE cases, showing a correlation coefficient of 0.81 (95 % CI: 0.71–0.88). Particularly, both the reported number of TBE cases and GT searches occurred mainly during the summer. The peak of disease notifications coincided with that of Google searches in 4 of 6 years. Once calibrated, SARIMA models with or without GT data were applied to a validation set. Retrospective forecast made by the model with GT data was associated with a lower prediction error and accurately predicted the peak timing. By contrast, the traditional SARIMA model underestimated the actual number of TBE notifications by 65 %. Timeliness, easy availability, low cost and transparency make monitoring of the TBE-related Internet search queries a promising addition to the traditional methods of TBE surveillance in Italy.