Oral human cytomegalovirus prevalence and its relationships with periodontitis and Porphyromonas gingivalis in Japanese adults: a cross-sectional study

This study aimed to clarify the association between oral human cytomegalovirus (HCMV) and periodontitis in Japanese adults. In total, 190 patients (75 men and 115 women; mean age, 70.2 years) who visited Hiroshima University Hospital between March 2018 and May 2020 were included. Oral rinse samples...

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Bibliographic Details
Published in:Journal of applied oral science 2020-01, Vol.28, p.e20200501-e20200501
Main Authors: Nakamura, Mariko, Shigeishi, Hideo, Cheng-Yih, S U, Sugiyama, Masaru, Ohta, Kouji
Format: Article
Language:English
Subjects:
Aged
Bacteroidaceae Infections - epidemiology
Coinfection
Cross-Sectional Studies
Cytomegalovirus
Cytomegalovirus Infections - epidemiology
Dentistry
DENTISTRY, ORAL SURGERY & MEDICINE
Female
Human Cytomegalovirus
Humans
Japan - epidemiology
Male
Original
Periodontal Pocket - microbiology
Periodontal Pocket - virology
Periodontitis
Periodontitis - epidemiology
Periodontitis - microbiology
Periodontitis - virology
Porphyromonas gingivalis
Prevalence
Real-time PCR
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Summary:This study aimed to clarify the association between oral human cytomegalovirus (HCMV) and periodontitis in Japanese adults. In total, 190 patients (75 men and 115 women; mean age, 70.2 years) who visited Hiroshima University Hospital between March 2018 and May 2020 were included. Oral rinse samples were taken to examine the presence of HCMV DNA using real-time polymerase chain reaction (PCR). P. gingivalis was detected by semi-quantitative PCR analysis. HCMV DNA was present in nine of 190 patients (4.7%). There were significant associations between HCMV presence and the presence of ≥4-mm-deep periodontal pockets with bleeding on probing (BOP) (P
ISSN:1678-7757
1678-7765
1678-7765
DOI:10.1590/1678-7757-2020-00501