KNOWLESI MALARIA IN MONKEYS II. A FIRST STEP IN THE SEPARATION OF THE MECHANICAL PATHOLOGIC CIRCULATORY FACTORS OF ONE SLUDGE DISEASE FROM POSSIBLE SPECIFIC TOXIC FACTORS OF THAT DISEASE

The fundamental purpose of this paper is to introduce a rigorous experimental method for separating and determining the significance of individual sets of mechanisms of the pathologic physiology of certain disease states. The contrast is noted between the visible circulatory factors in completely he...

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Bibliographic Details
Main Authors: Knisely,Melvin H, Stratman-Thomas,Warren K, Eliot,Theodore S, Bloch,Edward H
Format: Report
Language:English
Subjects:
BLOOD CIRCULATION
BLOOD COAGULATION
DISEASES
HEMOSPORIDIA
HEPARIN
MONKEYS
PARASITIC DISEASES
PATHOLOGY
PHYSIOLOGY
RETICULOENDOTHELIAL SYSTEM
TOXINS AND ANTITOXINS
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Summary:The fundamental purpose of this paper is to introduce a rigorous experimental method for separating and determining the significance of individual sets of mechanisms of the pathologic physiology of certain disease states. The contrast is noted between the visible circulatory factors in completely healthy-normal rhesus monkeys and in monkeys which are dying of Stage III Knowlesi malaria, a condition in which the blood is very severely agglutinated. Pub. in Angiology v15 n9 p411-16 Sep 1964 (Copies not available to DDC or Clearinghouse customers). Prepared in cooperation with Tennessee Univ., Memphis.