EXPERIMENTAL STUDY OF ACUTE AND CHRONIC INJURY TO RENAL TUBULES

The work carried out was multifaceted, dealing with the many factors concerned in acute and chronic injury to renal tubules. In view of the fact that most tubular lesions are the consequence of vascular impairment, many of the studies involved an examination of the behavior of arteries, arterioles a...

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Bibliographic Details
Main Authors: Heptinstall,Robert H, Mostofi,F. K
Format: Report
Language:English
Subjects:
ACIDOSIS
Anatomy and Physiology
ARTERIES
BLOOD CIRCULATION
CELLS(BIOLOGY)
DISEASES
ELECTRON MICROSCOPY
ESCHERICHIA COLI
HEMATOLOGY
HEMOGLOBIN
HYPERTENSION
KIDNEYS
Medicine and Medical Research
NECROSIS
PHOSPHORIC MONOESTER HYDROLASES
RENAL TUBULES
RETICULOENDOTHELIAL SYSTEM
STIMULATION(PHYSIOLOGY)
THYROID GLAND
WOUNDS AND INJURIES
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Summary:The work carried out was multifaceted, dealing with the many factors concerned in acute and chronic injury to renal tubules. In view of the fact that most tubular lesions are the consequence of vascular impairment, many of the studies involved an examination of the behavior of arteries, arterioles and glomeruli in the face of different stimuli. The juxtaglomerular apparatus is intimately concerned in the regulation of blood flow and experiments were carried out to shed light on this structure. The factors concerned in the stimulus for hyperplasia of the juxtaglomerular apparatus were studied to test the validity of the notion that the tonicity of the filtrate acting on the macula densa is of importance. (Author)