A Replication of Infectious Viral Ribonucleic Acid in Isolated Mitochondrias. Report II. A Replication of Viral Ribonucleic Acid in Mitochondrias and a Characteristic of the End Product

It was determined that the replication of viral infectious RNA in isolated mitochondrias is possible. An effective concentration of actinomycin D facilitated the detection of the synthesis of virus-specific RNA: 40S corresponding to virion, heterogenous area of 26-20S RNA with RNA-ase-resistant comp...

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Bibliographic Details
Main Authors: Ershov,F I, Gaitskhoki,V S, Kiselev,O I, Zaitseva,O V, Menshikh,L K
Format: Report
Language:English
Subjects:
ACTINOMYCIN
Biochemistry
BIOPHYSICS
BIOSYNTHESIS
DENSITY
DENSITY GRADIENT SEPARATION
GROWTH(GENERAL)
Microbiology
MITOCHONDRIA
SEDIMENTATION
TRANSLATIONS
USSR
VIRUSES
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Summary:It was determined that the replication of viral infectious RNA in isolated mitochondrias is possible. An effective concentration of actinomycin D facilitated the detection of the synthesis of virus-specific RNA: 40S corresponding to virion, heterogenous area of 26-20S RNA with RNA-ase-resistant component in the area of 20S which is supposed to be a replicative form. The dynamics of the synthesis of virus-specific RNA in mitochondria and the correlation of this process with the growth of the infectious product have been studied. (Author) Trans. of Voprosy Virusologii (USSR) v16 n3 p274-280 1971.