Yucatan Miniature Swine as an Animal Model for Dengue-1 Disease

Currently there is no animal model for dengue disease. Non-human primates and mice have been useful for vaccine efficacy studies, but they do not reproduce human disease. Yucatan Miniature swine were examined as a novel animal species in which to study dengue virus infection, resultant immune respon...

Full description

Saved in:
Bibliographic Details
Main Author: Robinson,Jaimie S
Format: Report
Language:English
Subjects:
dengue
Disease vectors
Infectious diseases
Laboratory animals
swine
Yucatan Miniature swine
Online Access:Request full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Currently there is no animal model for dengue disease. Non-human primates and mice have been useful for vaccine efficacy studies, but they do not reproduce human disease. Yucatan Miniature swine were examined as a novel animal species in which to study dengue virus infection, resultant immune responses, protective efficacy of the immune responses, and signs of illness with the aim of identifying an animal model for dengue disease. [truncated]