The Genomic Evolution of Prostate Cancer

The goal of this research proposal is to characterize the oncogenesis of prostate cancer and to more fully understand the relationship between clinically benign and aggressive disease. With help from my mentors I have identified four areas where I will focus my training during the completion of the...

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Bibliographic Details
Main Author: VanderWeele, David J
Format: Report
Language:English
Subjects:
biological markers
biomedical research
exome sequencing
genetic variation
genetics
genomics
mutations
neoplasms
prostate cancer
tumor evolution
tumor heterogeneity
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Summary:The goal of this research proposal is to characterize the oncogenesis of prostate cancer and to more fully understand the relationship between clinically benign and aggressive disease. With help from my mentors I have identified four areas where I will focus my training during the completion of the proposed project: 1. To continue to acquire a comprehensive understanding of prostate cancer genomics. 2. To develop an understanding of evolutionary genomics and tumor evolution. 3. To develop skills in translational prostate cancer biomarker development. 4. To continue to develop laboratory management and grant writing skills.