Hazard Evaluation of Candidate Face Net Impregnant Ent-18059-Gb 3-Chloro-1-Propanol Carbanilate

A hazard evaluation of the candidate face net impregnant 3-chloro-1-propanol carbanilate (ENT-18059-Gb) was performed by means of laboratory animal studies using rats, rabbits and quail. The technical grade compound did not produce primary irritation when applied to the intact or abraded skin of rab...

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Bibliographic Details
Main Authors: Weeks,Maurice H, Lovre,Stanton C , Jr, Pope,Conrad R
Format: Report
Language:English
Subjects:
AEROSOLS
BIRDS
Carbanilates
Carbanilic acid/(chloropropyl-ester)
ENT-18059-Gb
EXPOSURE(PHYSIOLOGY)
EYE
IMPREGNATION
INGESTION(PHYSIOLOGY)
INHALATION
IRRITATING AGENTS
LABORATORY ANIMALS
LETHAL DOSAGE
PROTECTIVE MASKS
RATS
SKIN(ANATOMY)
Toxicology
WOUNDS AND INJURIES
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Summary:A hazard evaluation of the candidate face net impregnant 3-chloro-1-propanol carbanilate (ENT-18059-Gb) was performed by means of laboratory animal studies using rats, rabbits and quail. The technical grade compound did not produce primary irritation when applied to the intact or abraded skin of rabbits. No corneal injury, iritis or conjunctivitis was observed after a single application of technical grade compound to the eyes of rabbits. Data indicate little acute toxic hazard from accidental ingestion. Acute aerosol exposure of rats and subchronic aerosol inhalation exposures of rats and quail resulted experimentally in no deleterious effect.