Sequential Postmortem Changes of Glomeruli. Their Detection by Scanning Electron Microscopy

Postmortem changes were studied by scanning electron microscopy (SEM) in renal tissue from five species of animals. Specimens were collected at intervals up to 24 hours after death. Six distinct morphological alterations were identified in the renal glomerulus, including capillary loop constriction,...

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Bibliographic Details
Main Author: Langlinais, Paulette C
Format: Report
Language:English
Subjects:
ELECTRON MICROSCOPY
GLOMERULI
LABORATORY ANIMALS
Medicine and Medical Research
MORPHOLOGY(BIOLOGY)
PATHOLOGY
REPRINTS
TISSUES(BIOLOGY)
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Summary:Postmortem changes were studied by scanning electron microscopy (SEM) in renal tissue from five species of animals. Specimens were collected at intervals up to 24 hours after death. Six distinct morphological alterations were identified in the renal glomerulus, including capillary loop constriction, changes in microvillus morphological features, podocyte surface blebs, swelling or fusion of pedicels, podocyte erosion, and retraction or loss of pedicels. Glomerular size remained nearly constant in all five species. The results of these studies demonstrate that pathological evaluation by SEM of tissue specimens from the kidney is acceptable up to 60 minutes post mortem. Published in Archives of Pathology and Laboratory Medicine, v105 p482-486, Sep 1981.